China Factory Direct
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| CAS number | 6146-52-7 |
| Product name | 5-Nitroindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Prepared from indole via nitration; used in subsequent coupling or reduction reactions to construct bioactive molecules |
| Pharmaceuticals | Precursor for synthesizing serotonin analogues | Selectively reduced or hydrolyzed to 5-hydroxyindole derivatives for synthesis of neurotransmitter analogues |
| Pesticides | Heterocyclic scaffold for novel insecticides or fungicides | Serves as a nitrogen-containing heterocyclic intermediate in nucleophilic substitution or cyclization reactions to build pesticide active ingredients |
| Dyes | Synthesis of indole-containing fluorescent dyes | Acts as a chromophore unit; fluorescent groups are introduced via coupling or condensation reactions for biological labeling |
| Chemical Research | Functionalized indole derivative template for organic synthesis | Used to construct polycyclic heterocycles; serves as a substrate for metal-catalyzed cross-coupling or C–H activation reactions |
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Visually examine the sample's color and physical state (e.g., white to off-white crystalline powder) to determine compliance with standard requirements. |
| Identification | Infrared Spectroscopy (IR) | Measure the infrared absorption spectrum of the sample and compare it with reference spectra to confirm the presence of characteristic functional groups (e.g., nitro group, indole ring). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze chemical shifts and coupling constants of hydrogen atoms in the ¹H NMR spectrum to verify consistency of molecular structure. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC with a C18 column as the stationary phase and a UV detector (typically at 254–300 nm wavelength) to quantify the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate and detect potential organic impurities (e.g., unreacted starting materials, by-products) using gradient or isocratic elution; calculate impurity levels using area normalization or correction factor methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and measure mass loss to assess moisture and volatile content. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method or digital melting point apparatus to evaluate purity and crystal form consistency. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC to detect residual organic solvents (e.g., methanol, dichloromethane) that may remain from synthesis or purification processes. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Digest the sample and measure elemental concentrations of heavy metals such as lead, arsenic, cadmium, and mercury to ensure compliance with pharmacopoeial or regulatory limits. |
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 162–166 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.