China Factory Direct
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| CAS number | 6151-25-3 |
| Product name | Quercetin dihydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Antioxidant, anti-inflammatory, and anticancer research | Used in formulation development following extraction and purification |
| Dietary Supplement Industry | Active ingredient in dietary supplements | Microencapsulation or tablet/capsule manufacturing |
| Cosmetics Industry | Anti-aging and skin-soothing active ingredient | Nanoemulsification or liposomal encapsulation |
| Research Sector | Reference standard for natural flavonoid compounds | Purification and calibration via high-performance liquid chromatography |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm the presence of characteristic functional groups of dihydrate quercetin (e.g., hydroxyl, carbonyl, aromatic ring, etc.). |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilize the characteristic absorption peaks of dihydrate quercetin at specific wavelengths (e.g., around 256 nm and 370 nm) for qualitative identification. |
| Identification | Thin-Layer Chromatography (TLC) | Develop the sample and reference standard under identical conditions, then compare the Rf values and spot colors (commonly using developing agents such as aluminum chloride or ammonia vapor) for rapid identification. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase of methanol-water or acetonitrile-water (often containing a small amount of acid such as phosphoric acid or formic acid), and detect using a UV detector (typically around 370 nm). Quantify dihydrate quercetin content by external or internal standard method. |
| Assay | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measure absorbance at the maximum absorption wavelength and calculate content via a standard curve. Suitable for rapid quantification of high-purity samples, though with lower specificity than HPLC. |
| Related Substances/Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Use gradient elution to separate and detect potential degradation products (e.g., quercetin glycosides, oxidation products) and other organic impurities. Typically perform limit testing using area normalization or standard self-dilution methods. |
| Loss on Drying | Oven Drying Method (Thermogravimetric Analysis or Constant Temperature Drying) | Dry the sample at a specified temperature (e.g., 105°C) until constant weight, then calculate the percentage weight loss. Used to control moisture and volatile components, indirectly reflecting the state of crystalline water. |
| Sulfated Ash | High-Temperature Incineration Method | Incinerate the sample at high temperature (approximately 700–800°C), then weigh the residual ash to determine the content of inorganic impurities. |
| Water Content | Karl Fischer Titration | Highly specific method for accurately determining total water content (including crystalline and adsorbed water). Commonly used to precisely control whether the water content in dihydrate quercetin meets the requirement for a "dihydrate" structure. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range. Dihydrate quercetin typically dehydrates before melting; the melting range can serve as a reference indicator of purity. |
| Crystal Form / Hydration Confirmation | Thermogravimetric Analysis-Differential Scanning Calorimetry (TGA-DSC) | Use thermal analysis techniques to observe water loss steps and melting endothermic peaks, confirming the number of water molecules (e.g., two water molecules) and crystal form stability. |
| Crystal Form / Hydration Confirmation | X-Ray Powder Diffraction (XRPD) | Obtain the sample's diffraction pattern and compare it with the standard pattern of dihydrate quercetin to confirm its crystal structure and detect possible polymorphic transitions or amorphous impurities. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 312–316°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.