CHOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62-49-7 |
| Product name | CHOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for CHOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk CHOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of CHOLINE
| Industry | Application | Process |
|---|---|---|
| Animal Feed Additives | Nutritional supplement for animals, supporting lipid metabolism, liver health, and neural development | Added to premixes or complete feeds as choline chloride, typically in 50% or 75% aqueous solution or granular form |
| Food Industry | Nutritional fortificant (vitamin B4), emulsifier, and pH regulator | Incorporated directly into formulations for infant formula, sports drinks, and baked goods as choline salts (e.g., choline bitartrate, choline chloride) |
| Pharmaceutical Industry | Pharmaceutical excipient (solubilizer, permeation enhancer) and active pharmaceutical ingredient (for adjunctive treatment of hepatic and neurodegenerative disorders) | Used as a filler/binder in tablets and capsules; included as choline chloride in intravenous solutions; employed as a precursor in acetylcholine synthesis for cholinesterase inhibition studies |
| Cosmetics | Skin conditioning agent, humectant, and promoter of cellular repair | Formulated into anti-aging creams and conditioners as choline chloride or phosphocholine to stabilize the formulation and enhance stratum corneum penetration |
| Chemical Intermediates | Starting material for synthesizing acetylcholine, phosphatidylcholine, surfactants, and quaternary ammonium compounds | Converted into high-value choline derivatives via quaternization reactions (e.g., with ethylene oxide or chloromethane) |
Manufacturing Quality Control of CHOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Choline Content) | Acid-Base Titration | Quantifies choline hydroxide or choline chloride by titration with standardized acid or base using a suitable indicator or potentiometric endpoint. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric reaction between water and iodine in a methanol-based reagent. |
| pH (1% aqueous solution) | pH Potentiometry | Determines hydrogen ion activity using a calibrated pH electrode in a standardized aqueous solution. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals by atomization and measurement of absorbance at characteristic wavelengths. |
| Sulfate | Gravimetric Analysis | Precipitates sulfate as barium sulfate and determines content by weighing the dried precipitate. |
| Chloride | Potentiometric Titration | Titrates chloride with silver nitrate using a silver indicator electrode to detect endpoint. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic impurities by ignition at 500-600 C and weighing residual ash. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by choline solutions to assess enantiomeric purity and identity. |
| Related Substances | HPLC-UV | Separates and quantifies choline and its degradation products (e.g., trimethylamine, betaine) using reversed-phase chromatography and UV detection. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Iron (Fe) | ICP-OES | Quantifies iron by plasma excitation and emission intensity measurement at element-specific wavelengths. |
| Appearance (Solution Clarity) | Visual Inspection | Assesses clarity and absence of particulates in a specified concentration aqueous solution against standard reference. |
Technical Specifications of CHOLINE
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 238-242°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild fishy odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of CHOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of CHOLINE
Packaging of CHOLINE
Industrial CHOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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