China Factory Direct
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| CAS number | 62003-27-4 |
| Product name | bis(5-oxo-L-prolinato-N1,O2)magnesium |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical Industry | Used as a pharmaceutical intermediate in the synthesis of certain antiepileptic drugs and neuroprotective agents | Prepared via organic synthesis by reacting 2-pyrrolidone-5-carboxylic acid with a magnesium salt |
| Chemical Industry | Employed as a catalyst or intermediate in organic synthesis | Prepared by nucleophilic substitution between magnesium metal and 2-pyrrolidone-5-carboxylic acid |
| Polymer Materials | Applied as a crosslinking agent or functional monomer in the synthesis of polymers with specific performance characteristics | Incorporated into polymer chains via polymerization to enhance thermal stability and mechanical properties |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Assay (Main Component Analysis) | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with a mobile phase consisting of methanol-water or a phosphate/acetonitrile buffer system, detected by a UV detector (e.g., 220–254 nm). Quantification of the target compound is achieved by comparing retention time and peak area with a reference standard, suitable for purity and content determination. |
| Purity Analysis | Gas Chromatography (GC) (if applicable) or HPLC-MS | GC is suitable for volatile derivatives (e.g., after derivatization); however, magnesium 2-pyrrolidone-5-carboxylate is highly polar and generally unsuitable for GC. HPLC coupled with mass spectrometry (LC-MS) is recommended for high-sensitivity purity analysis, enabling simultaneous identification of impurities and degradation products. |
| Impurity Check (Related Substances) | HPLC (High-Performance Liquid Chromatography with UV/MS detection) | Optimized gradient elution protocols are employed to separate potential synthetic by-products, degradation products, or residual starting materials (e.g., pyrrolidone, glutamic acid derivatives). UV or MS detectors are used for qualitative and quantitative analysis to ensure compliance with pharmacopoeial or corporate standards. |
| Heavy Metal Testing | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, the content of heavy metals such as lead, cadmium, mercury, and arsenic is measured to ensure compliance with heavy metal limits for pharmaceutical or food-grade products as specified by USP, EP, or ChP. |
| Water Content Determination | Karl Fischer Titration | Applicable to samples containing water of crystallization or those prone to hygroscopy; precisely measures free or crystalline water content, critical for stability assessment and formulation processes. |
| Residue on Ignition (Ash Content) | High-Temperature Incineration (Muffle Furnace) | Sample is incinerated at high temperature (e.g., 500–600°C) to constant weight to determine the residual inorganic matter, reflecting the level of inorganic salt impurities. |
| pH Value Determination | pH Meter Method | According to the Chinese Pharmacopoeia or relevant standards, a solution of defined concentration is prepared and measured using a calibrated pH meter to ensure the product remains within the specified range (e.g., 6.0–8.0), which affects solubility and bioavailability. |
| Identification Test | Infrared Spectroscopy (IR) | Identification is based on characteristic absorption peaks (e.g., carbonyl νC=O ~1700 cm⁻¹, N-H stretching vibration ~3300 cm⁻¹, C-N bonds) by comparison with a reference spectrum, confirming molecular structure and functional group features for authenticity verification. |
| Molecular Weight Determination | Mass Spectrometry (MS, ESI-MS or MALDI-TOF) | Used to confirm molecular formula and molecular weight, particularly for complex structures or isomers; assists in verifying the expected magnesium salt form. |
| Crystalline Form Analysis | X-ray Diffraction (XRD) | Used to identify crystal structure, polymorphic forms, and their stability, which significantly influence drug dissolution behavior and formulation performance. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 195-200°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.