China Factory Direct
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| CAS number | 62129-44-6 |
| Product name | BOC-4-IODO-L-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral amino acid protecting reagent in peptide synthesis | Used as an N-terminal protecting group in solid-phase peptide synthesis (SPPS); the α-amino group is protected with a Boc group, and the iodinated aryl ring enables subsequent palladium-catalyzed cross-coupling (e.g., Suzuki, Heck reactions) to introduce functionalized side chains |
| Organic Synthesis | Construction of iodinated aryl chiral building blocks | Applied in asymmetric catalysis, molecular probe development, and synthesis of targeted drug intermediates; the iodine atom serves as a leaving group in nucleophilic substitution or metal-catalyzed C–C bond formation |
| Biochemical Research | Structural unit for fluorescent labeling or multimodal probes | Radioiodinated (e.g., with 125I) via the iodine atom for receptor binding assays, PET imaging precursors, or mass spectrometry internal standards |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities via retention time comparison and peak area integration. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies metal contaminants (e.g., Pb, Cd, Ni) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in laser light scattering from dispersed particles. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in saturated aqueous suspension using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration and Culture | Detects aerobic microorganisms by filtration, membrane transfer to growth media, and colony enumeration. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | +22.5±3.0° (c=1, in DMF) |
| Identification (NMR) | Conforms to reference spectrum |
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| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.