H-HYP-OBZL HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62147-27-7 |
| Product name | H-HYP-OBZL HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-HYP-OBZL HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-HYP-OBZL HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-HYP-OBZL HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antiviral agents (e.g., HIV protease inhibitors) and collagen-mimetic peptides | Employed as a chiral building block, incorporated at the N-terminus or side chain of peptide sequences via deprotection and coupling steps |
| Organic Synthesis | Used as a chiral auxiliary or substrate for asymmetric synthesis | Participates in asymmetric alkylation, cycloaddition, and other reactions, leveraging the directing effect of its rigid pyrrolidine ring and hydroxyl group |
| Biochemical Research | Used as a labeled probe for collagen metabolism studies and as a model compound for prolyl hydroxylase inhibition | Substitutes for natural L-4-hydroxyproline in cellular or enzymatic assays to monitor hydroxylation kinetics |
Manufacturing Quality Control of H-HYP-OBZL HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; trans-L-4-hydroxyproline benzyl ester hydrochloride is quantified relative to its D-isomer impurity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify benzyl alcohol, methanol, ethyl acetate, and other process solvents. |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis after acid digestion, measuring Pb, Cd, Hg, As, and Ni at sub-ppb levels. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration from hydrochloride salt. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-benzylated product, diastereomers, oxidation products) using gradient HPLC. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation at 589 nm using a polarimeter to confirm stereochemical identity and batch consistency. |
| pH (1% aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous solution at 25 C. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after controlled ashing at 700-800 C. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via light scattering to determine D10, D50, D90 values. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of H-HYP-OBZL HCL
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 168~172°C |
| Optical Rotation | -39~-35° (c=1, in 1M HCl) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-HYP-OBZL HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-HYP-OBZL HCL
Packaging of H-HYP-OBZL HCL
Industrial H-HYP-OBZL HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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