(S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6216-63-3 |
| Product name | (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates | Used as asymmetric synthesis intermediates for chiral drugs, including antiviral agents and protease inhibitors |
| Chemical synthesis | Chiral auxiliaries | Employed as chiral auxiliaries in asymmetric catalytic reactions, such as Sharpless dihydroxylation and Diels–Alder reactions |
| R&D | Organic synthesis building blocks | Applied to construct complex molecules containing proline motifs, including peptide mimetics and biologically active compounds |
Manufacturing Quality Control of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase followed by UV quantification relative to the main enantiomer. |
| Water Content | Karl Fischer titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based solvent system. |
| Residual Solvents | Gas Chromatography (GC) with FID | Separation and quantification of volatile organic solvents using capillary column GC and flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of metal impurities after acid digestion, based on element-specific atomic emission intensities. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity-based detection of chloride anions in aqueous extract. |
| Sulfated Ash | Gravimetric analysis | Combustion at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary melting point apparatus | Determination of temperature range over which solid transitions to liquid, indicating purity and identity. |
| pH of Aqueous Solution | pH meter | Electrochemical measurement of hydrogen ion activity in a defined aqueous suspension or solution. |
| Related Substances | HPLC with UV detection | Detection and quantification of structurally related impurities using gradient elution and UV absorbance at multiple wavelengths. |
Technical Specifications of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -42.5 to -42.3 deg (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
Safety Information of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE
Industrial (S)-1-CBZ-2-HYDROXYMETHYLPYRROLIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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