4-Hydroxybenzyl alcohol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 623-05-2 |
| Product name | 4-Hydroxybenzyl alcohol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Hydroxybenzyl alcohol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Hydroxybenzyl alcohol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Hydroxybenzyl alcohol
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Drug Synthesis | Used as an intermediate in the synthesis of anti-inflammatory drugs, antipyretic analgesics, and other pharmaceuticals |
| Cosmetics Industry | Preservative | Applied as a preservative in cosmetic formulations to inhibit microbial growth |
| Chemical Industry | Fragrance Synthesis | Employed as a raw material for synthesizing various fragrances, including rose-scented compounds |
| Research | Biochemical Research | Utilized as a laboratory reagent in biochemical research, including studies on cellular signal transduction and other biochemical processes |
| Materials Science | Polymer Synthesis | Used as a monomer or modifier in the synthesis of certain polymers |
Manufacturing Quality Control of 4-Hydroxybenzyl alcohol
| Milestone | Common Testing Methods | Method Overview |
|---|---|---|
| Purity and Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a C18 reversed-phase column, with methanol-water or acetonitrile-water as the mobile phase, detected by UV detector (275–280 nm). Quantitative analysis is performed using external standard method or internal standard method. It can simultaneously detect impurities, with high accuracy, and is the mainstream method in pharmacopoeia. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Refer to General Chapter 0612 of the Chinese Pharmacopoeia. The sample is placed into a capillary tube and heated slowly. The melting range (literature value approximately 130–133°C) is recorded, used for preliminary identification and purity assessment. |
| Moisture Determination | Karl Fischer Titration (KF Method) | The Karl Fischer reagent composed of iodine, sulfur dioxide, pyridine, and methanol reacts quantitatively with water. The titration is determined by potentiometric or endpoint indication, suitable for trace moisture detection (usually required ≤0.5%). |
| Heavy Metal Testing | Atomic Absorption Spectrometry (AAS) or ICP-MS | After sample digestion, heavy metal content such as lead, cadmium, and mercury is measured by AAS, or multi-element simultaneous detection is performed by ICP-MS. It meets the heavy metal limit requirements of the pharmacopoeia (e.g., ≤10 ppm). |
| Inorganic Impurities (e.g., Chlorides, Sulfates) | Turbidimetry or Ion Chromatography | Chloride is analyzed by silver nitrate turbidimetry (Pharmacopoeia General Chapter 0801), and sulfate by barium chloride turbidimetry; ion chromatography can also be used for high sensitivity and simultaneous multi-ion detection. |
| Related Substances (Impurity Profile) | HPLC-UV or HPLC-MS | HPLC method with gradient elution separates degradation products (such as p-hydroxybenzaldehyde, p-hydroxybenzoic acid), detected by UV. Or combined with mass spectrometry (LC-MS) for structural identification, ensuring that the total impurity level conforms to regulations (e.g., ≤1.0%). |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | A solution is prepared in ethanol or water, and the maximum absorption peak at 275–280 nm is measured, used for qualitative identification and rapid concentration estimation (quantitative after correction). |
| Solvent Residues (e.g., Ethanol, Methanol) | Gas Chromatography (GC-FID) | Headspace or direct injection, using a polar capillary column (e.g., DB-WAX), detected by FID. Quantification of residual organic solvents follows the pharmacopoeia guidelines on residual solvents (e.g., ICH Q3C). |
| Identification Test | Fourier Transform Infrared Spectroscopy (FT-IR) | Compared with the standard spectrum, characteristic absorption peaks include: 3200–3500 cm⁻¹ (phenolic O-H), 1600, 1500 cm⁻¹ (benzene ring framework), 1270 cm⁻¹ (C-O stretching), etc. |
| Polymorphic Form (if applicable) | X-ray Powder Diffraction (XRPD) | Used to distinguish different polymorphic forms (for polymorphic drugs, control is required). The consistency of the polymorphic form is confirmed by comparing the position and intensity ratio of characteristic diffraction peaks. |
Technical Specifications of 4-Hydroxybenzyl alcohol
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 115.0–119.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Hydroxybenzyl alcohol
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NMR Spectra of 4-Hydroxybenzyl alcohol
Packaging of 4-Hydroxybenzyl alcohol
Industrial 4-Hydroxybenzyl alcohol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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