2,6-Dimethoxypyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6231-18-1 |
| Product name | 2,6-Dimethoxypyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,6-Dimethoxypyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,6-Dimethoxypyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,6-Dimethoxypyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the anticancer drug irinotecan | Used to construct the irinotecan core scaffold via multi-step reactions including condensation and cyclization with 4-piperidone |
| Agrochemicals | Structural modification unit for novel herbicides and insecticides | Integrated as a heterocyclic scaffold into active molecules to enhance target binding affinity and metabolic stability |
| Materials Science | Building block for electron-transport layer materials in organic light-emitting diodes (OLEDs) | Incorporated into conjugated polymer backbones via Suzuki or Ullmann coupling to modulate HOMO/LUMO energy levels |
| Chemical Synthesis | Ligand precursor for metal-catalyzed cross-coupling reactions | After lithiation and borylation, employed in Suzuki, Hiyama, and related coupling reactions to improve palladium catalyst stability |
Manufacturing Quality Control of 2,6-Dimethoxypyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~240 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of impurities (e.g., mono-methoxy analogs, pyridine N-oxide, residual solvents) using gradient elution and UV detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Heating sample to 700–800 °C and measuring inorganic residue as mass percent after combustion of organic matter. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of trace metals (e.g., Pb, Cd, Hg, As) after acid digestion, using plasma-based elemental detection with multi-element capability. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions via suppressed conductivity detection (IC), or direct titration with silver nitrate. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 589 nm to confirm enantiomeric purity (though compound is achiral, used for batch consistency and chiral contaminant screening). |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization or mass spectrometric detection to quantify solvents (e.g., methanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Measurement of hydrogen ion activity in a saturated aqueous slurry to assess acidic/basic degradation products or residual catalysts. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dry or dispersed state using Mie scattering theory to ensure consistent handling and dissolution behavior. |
Technical Specifications of 2,6-Dimethoxypyridine
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 35–37°C |
| Refractive Index (n20/D) | 1.525–1.535 |
| Relative Density (20°C/4°C) | 1.090–1.110 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,6-Dimethoxypyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,6-Dimethoxypyridine
Packaging of 2,6-Dimethoxypyridine
Industrial 2,6-Dimethoxypyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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