L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6234-01-1 |
| Product name | L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediate | Used in asymmetric synthesis of peptide-based therapeutics and β-lactam antibiotics as a key raw material for constructing chiral centers |
| Organic synthesis | Amino acid protecting reagent | Enables selective protection and deprotection during peptide chain elongation, leveraging its tert-butyl ester group and hydrochloride salt form |
| Pharmaceutical manufacturing | Antitumor drug precursor | Involved in synthesizing biologically active glutamic acid derivatives for targeted drug development |
| Biochemical research | Biochemical reagent preparation | Applied in synthesizing fluorescent labels or probe molecules to study cellular uptake mechanisms and metabolic pathways |
Manufacturing Quality Control of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., diastereomers, hydrolysis products) using gradient HPLC-UV against reference standards or threshold-based reporting. |
| Optical Rotation | [alpha]D | Measures specific rotation in solution using a polarimeter to confirm chiral integrity and enantiomeric excess. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., methanol, THF, ethyl acetate) by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generated electrochemically or added reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Screens for toxic elements (Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Chloride Content | Potentiometric Titration | Quantifies chloride ions using silver nitrate titrant and silver/silver chloride indicator electrode, detecting endpoint via potential change. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual non-volatile material. |
| pH (1% w/v aqueous solution) | pH Meter | Measures hydrogen ion activity in aqueous suspension using calibrated glass electrode pH meter under controlled temperature. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against defined standards (e.g., white to off-white crystalline powder, free from visible particulates). |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Microbial Contamination | Membrane Filtration | Tests for aerobic microorganisms by filtering sample through sterile membrane, then culturing on soybean-casein digest agar under controlled conditions. |
Technical Specifications of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (NMR) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +24.0 to +27.0 deg (c=1, H2O) |
| Melting Point | 178 to 182 °C |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
Safety Information of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride
Industrial L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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