Boc-D-Aspartic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62396-48-9 |
| Product name | Boc-D-Aspartic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Boc-D-Aspartic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Boc-D-Aspartic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Boc-D-Aspartic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D and Manufacturing | Chiral drug synthesis intermediate for preparing D-aspartic acid–derived peptide therapeutics and enzyme inhibitors | N-tert-butoxycarbonylation protection with Boc₂O under basic conditions (e.g., NaOH, NaHCO₃) or organic bases (e.g., DIPEA) in inert solvents (e.g., THF, DMF); subsequent deprotection under acidic conditions (e.g., TFA/DCM) for participation in solid-phase peptide synthesis (SPPS) or solution-phase coupling |
| Peptide Synthesis | D-configured amino acid building block for constructing biologically active peptides containing D-aspartic acid (e.g., antimicrobial peptides, hormone analogs) | Used as a Boc-protected monomer in Fmoc/Boc dual-protection strategies; coupled to the N-terminus of resin-bound peptide chains on solid-phase peptide synthesizers using activators (e.g., HBTU/HOBt/DIPEA) |
| Biochemical Research | Studying the role of D-amino acids in protein structure, enzyme substrate specificity, and metabolic pathways | Served as a source of D-aspartic acid in in vitro enzymatic reactions or cell culture systems; employed with isotopic labeling (e.g., ¹³C-Boc-D-Asp) for metabolic flux analysis or NMR structural elucidation |
Manufacturing Quality Control of Boc-D-Aspartic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by reversed-phase HPLC with UV detection at 210 nm, using external standard calibration. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase, with UV detection for enantiomeric excess calculation. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on stoichiometric reaction. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to volatilize organic matter, then weighing inorganic residue. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other metals after acid digestion and plasma emission spectroscopy. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Boc-Asp-OH diastereomers, deprotected Asp) using gradient HPLC. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after drying at 105 C under vacuum or nitrogen to determine volatile content. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral identity and enantiomeric integrity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a defined aqueous suspension or solution using calibrated pH electrode. |
| Residual Solvents | GC-FID | Quantification of residual solvents (e.g., DMF, THF, ethyl acetate) by gas chromatography with flame ionization detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic microorganisms via filtration, membrane transfer, and incubation on appropriate agar media. |
Technical Specifications of Boc-D-Aspartic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C (decomposes) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | +17.0 to +19.0° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Boc-D-Aspartic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Boc-D-Aspartic acid
Packaging of Boc-D-Aspartic acid
Industrial Boc-D-Aspartic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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