China Factory Direct
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| CAS number | 62459-02-3 |
| Product name | 7-BENZYL-5,6,7,8-TETRAHYDROPYRIDO[3,4-D]PYRIMIDINE-2,4(1H,3H)-DIONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a pharmaceutical intermediate for synthesizing biologically active pyrimidine compounds | Organic synthesis reactions, including condensation and cyclization steps |
| Organic Synthesis | Employed as a key intermediate in the synthesis of fine chemicals | Multi-step synthetic routes involving nucleophilic substitution and reductive amination |
| Biochemical Research | Applied in constructing molecular probes or analogs to study enzyme inhibitor mechanisms | Advanced organic synthesis and structural modification techniques |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm the presence of characteristic functional groups (e.g., amide, pyrimidine ring, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use ¹H NMR to measure chemical shifts, integration areas, and coupling constants of hydrogen atoms in the compound to verify structural features. | |
| Mass Spectrometry (MS) | Obtain molecular ion and fragment ions via electrospray ionization (ESI) or electron ionization (EI) to confirm molecular weight and structural information. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol/acetonitrile-water (containing buffer salt or acid) as mobile phase and a UV detector (e.g., 254 nm) to quantify the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Using the same conditions as assay or a gradient elution program to separate and detect process impurities, degradation products, etc. Quantify using area normalization or relative response factors. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection, using polar or non-polar capillary columns with FID detector, in accordance with ICH Q3C guidelines to detect residual organic solvents (e.g., methanol, dichloromethane, DMF, etc.). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) to constant weight and calculate the percentage loss of moisture or other volatile components by mass. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method or digital melting point apparatus as an auxiliary indicator of purity and identity. |
| Specific Optical Rotation (if chiral) | Polarimeter | If the compound has chiral centers and stereochemistry control is required, optical purity can be assessed by measuring optical rotation. |
| pH Value (if prepared as solution) | pH Meter | Dissolve the sample into an aqueous solution of defined concentration and measure its pH to evaluate whether acidity or alkalinity meets specifications. |
| Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | According to ICH Q3D requirements, detect potential heavy metal elemental impurities (e.g., catalyst residues such as Pd, Ni, etc.). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 210–215 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.