4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62501-45-5 |
| Product name | 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a building block for synthesizing pyrimidine derivatives in the production of anticancer, antiviral, or antibacterial agents |
| Pharmaceutical Chemicals | Modification of Thiourea Compounds | Converts thiocarbonyl groups into thioethers or other functional groups via alkylation or acylation, enabling construction of pharmacologically active molecular scaffolds |
| Chemical Reagents | Research Reagents | Used for structural modification and biological activity screening at laboratory scale |
Manufacturing Quality Control of 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., des-thiol analogs, oxidation products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection (or mass spectrometry) for identification and quantification of solvents (e.g., methanol, acetone, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous pyridine/methanol medium; suitable for low-level moisture determination (<0.5%). |
| Heavy Metals | ICP-MS or AAS (after acid digestion) | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) following microwave-assisted nitric acid digestion and elemental analysis by inductively coupled plasma mass spectrometry or atomic absorption spectroscopy. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration using silver nitrate solution with a silver indicator electrode; measures free Cl⁻ arising from excess HCl or hydrolysis byproducts. |
| pH (1% w/v aqueous suspension) | pH Meter Measurement | Electrochemical measurement of hydrogen ion activity in a standardized aqueous suspension, reflecting residual acidity and salt stability. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | High-temperature incineration (600–700 °C) followed by weighing of non-volatile inorganic residue, indicating inorganic impurities or counterion-related ash. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volume-based particle size distribution in dispersed solid samples. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via visual observation of solid-to-liquid phase change under controlled heating; used for identity and purity verification. |
| Identity Confirmation | FT-IR Spectroscopy | Comparison of characteristic vibrational absorption bands (e.g., C=S, N–H, C–N) against a reference spectrum for structural confirmation. |
| Organic Volatile Impurities (e.g., Dioxane, Benzene) | GC-MS (Headspace) | Targeted screening and quantification of genotoxic solvents using headspace sampling and mass-selective detection per ICH Q3A(R2). |
Technical Specifications of 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 192-196°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride
Industrial 4,6-dimethyl-1H-pyrimidine-2-thione hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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