China Factory Direct
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| CAS number | 625120-81-2 |
| Product name | 3-(N-Methylpentylamino)propionic acid hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing drug molecules | Organic synthesis reactions, such as amidation and alkylation |
| Biochemical Research | Model compound for studying neurotransmitter or receptor binding | Preparation of molecular probes and biological activity testing |
| Advanced Materials | Synthesis of functionalized polymers or surface modifiers | Polymerization or coupling reaction processes |
| Organic Synthesis | Amine precursor in multistep syntheses | Reaction with acid anhydrides or alkyl halides to yield target products |
| Detection Item | Common Testing Methods | Method Overview |
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| Appearance and Physical Form | Visual Inspection | Observe that the sample appears as a white to off-white crystalline powder, free of visible foreign particles, consistent with the specified physical state. |
| Identification | Infrared Spectroscopy (IR) | Compare the infrared spectrum of the sample with that of the reference standard to confirm the presence of characteristic functional groups (e.g., carboxylate, amine salt, C-N bond). |
| High-Performance Liquid Chromatography (HPLC) | Compare retention time with that of the reference standard to confirm identity of the main component (using C18 column, UV detection at 210–220 nm). | |
| Nuclear Magnetic Resonance Spectroscopy (¹H NMR) | Measure in D₂O or DMSO-d₆ solvent to confirm chemical shifts and integration ratios of methyl, methylene, amine groups, and propionic acid chain within the structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Quantify the main component using external standard or internal standard method with UV detector (210–220 nm); linear range: 0.05–2.0 mg/mL, R² ≥ 0.999. |
| Non-aqueous Titration | Use glacial acetic acid as solvent and perchloric acid as titrant, with crystal violet as indicator, to determine free amine content in the hydrochloride salt; suitable when no UV absorption interference is present. | |
| Impurity Profiling | High-Performance Liquid Chromatography (HPLC-UV/DAD) | Use gradient elution to separate potential impurities (e.g., unreacted starting materials, demethylated products, oxidation products, hydrolysis byproducts), with detection limit ≤ 0.1%. |
| Liquid Chromatography-Mass Spectrometry (LC-MS) | Perform structural elucidation of unknown impurities detected by HPLC, providing molecular weight and fragmentation information for impurity assignment. | |
| Water Content | Karl Fischer Titration | Determine water content using coulometric or volumetric Karl Fischer method; controlled at ≤ 0.5% (adjusted according to stability requirements). |
| Residual Solvents | Gas Chromatography (GC) | Detect solvents such as ethanol, acetone, dichloromethane according to ICH Q3C guidelines, meeting specified limits. |
| Chloride Ion Content | Ion Chromatography (IC) or Precipitation Titration | Determine chloride ion concentration via ion chromatography or silver nitrate titration; should match theoretical value (theoretical Cl⁻ ≈ 24.5%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect residual heavy metals (Pb, Cd, Hg, As), complying with ICH Q3D or pharmacopoeial limits (e.g., Pb ≤ 10 ppm). |
| pH (Solution) | pH Meter Measurement | Prepare a 1% aqueous solution and measure pH, typically ranging from 4.0 to 6.0 (characteristic of hydrochloride salt). |
| Solubility | Shake Flask Method | Determine solubility in water, ethanol, DMSO, etc., for use in formulation development. |
| Particle Size Distribution (if applicable) | Laser Diffraction | For powder formulations or products requiring flowability control, determine particle size parameters such as D50 and D90. |
| Microbial Limits (for pharmaceutical use) | Plate Count Method | Test for total aerobic microbial count, mold and yeast, and Escherichia coli; comply with non-sterile drug substance standards (e.g., ChP 1107). |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.