(S)-3-Amino-1-N-Boc-piperidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 625471-18-3 |
| Product name | (S)-3-Amino-1-N-Boc-piperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-3-Amino-1-N-Boc-piperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-3-Amino-1-N-Boc-piperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-3-Amino-1-N-Boc-piperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Chiral intermediate for synthesizing antidepressants, antipsychotics, and central nervous system (CNS) drugs | Preparation of the (S)-enantiomer via asymmetric synthesis or chiral resolution, followed by Boc protecting group introduction |
| Biopharmaceuticals | Building block for peptide-based therapeutics and targeted therapeutic molecules | Participation in coupling reactions—such as Suzuki coupling or amide bond formation—via its amino group and piperidine ring |
| Chemical Research | Chiral catalyst or ligand precursor for asymmetric reaction studies | Generation of functionalized piperidine derivatives through deprotection or derivatization, applied in organic synthesis catalytic systems |
| Advanced Materials | Monomer design for functionalized polymeric materials | Incorporation of the piperidine scaffold via polymerization (e.g., ring-opening polymerization) to enhance thermal stability and biocompatibility |
Manufacturing Quality Control of (S)-3-Amino-1-N-Boc-piperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of (S)- and (R)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., MeOH, EtOAc, THF) using flame ionization detection with headspace sampling. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Boc Reagent | GC-FID | Detection and quantification of di-tert-butyl dicarbonate (Boc2O) by gas chromatography with flame ionization detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-Boc product, N-oxide, dimers) using gradient reversed-phase HPLC. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation at 20 C using sodium D-line (589 nm) to confirm chiral integrity and concentration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition analysis by controlled heating; onset and range indicate crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against established reference standards under controlled lighting. |
| pH (1% w/v aqueous suspension) | pH Meter | Measurement of hydrogen ion activity in aqueous suspension using calibrated pH electrode; reflects residual acidic/basic impurities. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile inorganic residue after high-temperature ashing at 750 C; indicates inorganic salt content. |
Technical Specifications of (S)-3-Amino-1-N-Boc-piperidine
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to orange clear liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +27.0 to +34.0 deg (c=1, in methanol) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-3-Amino-1-N-Boc-piperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-3-Amino-1-N-Boc-piperidine
Safety Information of (S)-3-Amino-1-N-Boc-piperidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (S)-3-Amino-1-N-Boc-piperidine
Industrial (S)-3-Amino-1-N-Boc-piperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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