4-Bromo-D-phenylalanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62561-74-4 |
| Product name | 4-Bromo-D-phenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-D-phenylalanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-D-phenylalanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-D-phenylalanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Raw material for peptide drug synthesis | Serves as a non-natural amino acid monomer in solid-phase or solution-phase peptide synthesis to construct peptide-based drug molecules with specific pharmacological activity (e.g., modulation of receptor binding affinity). |
| Pharmaceutical Chemicals | Intermediate for small-molecule drug synthesis | Used in the synthesis of targeted therapeutics or inhibitors; the bromine substituent enables subsequent coupling reactions (e.g., Suzuki coupling) to introduce aryl groups. |
| Biotechnology | Preparation of biological probes and labeling reagents | The bromo substituent serves as a reactive site for click chemistry or crosslinking reactions to conjugate fluorescent tags or biotin labels to phenylalanine derivatives. |
| Scientific Research | Protein structure and function studies | Incorporated as a structural analog into proteins for NMR-based structural analysis or for investigating enzyme stereoselectivity and catalytic mechanisms. |
| Scientific Research | Synthesis of chiral ligands for asymmetric catalysis | Serves as a chiral building block for synthesizing enantiomerically enriched organic ligands used in metal-catalyzed asymmetric synthesis reactions. |
Manufacturing Quality Control of 4-Bromo-D-phenylalanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase, with UV detection and calculation of enantiomeric excess from peak areas. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) based on calibrated external standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace metal impurities. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration using iodine generated in situ to determine trace water content based on stoichiometric reaction with water. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (500–600 °C) and weighing. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution at 20 °C using sodium D-line (589 nm), confirming chiral identity and batch consistency. |
| Related Substances (Impurities) | HPLC-UV (Forced Degradation Compatible) | Detection and quantification of structurally related impurities (e.g., des-bromo analog, diastereomers, hydrolysis/degradation products) using gradient HPLC-UV. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated pH electrode in a standardized aqueous suspension/solution to assess acid-base characteristics. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine D10, D50, D90 values per ISO 13320. |
| Microbial Limits | Membrane Filtration + Culture Enumeration | Quantitative assessment of total aerobic microbial count and absence of specified pathogens (e.g., E. coli, Salmonella) per Ph. Eur. 5.1.4. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate (e.g., 1 °C/min). |
Technical Specifications of 4-Bromo-D-phenylalanine
| Test Item | Specification |
|---|---|
| Appearance | Yellow powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 245–249 °C |
| Optical Rotation | +18.0 to +20.0 ° (c=1, in 6N HCl) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-D-phenylalanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-D-phenylalanine
Packaging of 4-Bromo-D-phenylalanine
Industrial 4-Bromo-D-phenylalanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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