China Factory Direct
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| CAS number | 62561-75-5 |
| Product name | 4-IODO-D-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a precursor for synthesizing radiolabeled drugs in positron emission tomography (PET) tracer development | Integrated into the phenylalanine structure via iodine isotopes (e.g., ¹²³I or indirect ¹⁸F labeling) for tumor or neuroreceptor imaging |
| Biochemical Research | Employed as a non-canonical amino acid in protein engineering and enzymology studies | Leverages steric hindrance and electronic properties to modulate protein conformation or active-site functionality of enzymes |
| Radiopharmaceuticals | Applied in preparing radioprobes targeting amino acid transporters (e.g., LAT1) | Coupled with radioactive iodine isotopes and administered intravenously for in vivo metabolic imaging |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase, with UV detection and calculation of enantiomeric excess from peak areas. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, DMF) against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace heavy metals after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Residue on Ignition | Gravimetric Analysis | Ignition of sample at 700–800 °C followed by weighing of inorganic residue to assess inorganic impurities. |
| Specific Optical Rotation | [α]D | Measurement of optical rotation using a polarimeter at 20 °C with sodium D-line (589 nm), reported as degrees per dm·g/mL to confirm chiral identity and purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via laser light scattering to determine D10, D50, and D90 particle size parameters. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., deiodinated analog, oxidation products) using gradient HPLC-UV under stressed conditions (acid, base, heat, oxidation). |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, Salmonella) per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -22.0 to -24.0° (c=1, in 6N HCl) |
| Melting Point | 245 to 249°C (dec.) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.