4-CHLOROBUTYRIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 627-00-9 |
| Product name | 4-CHLOROBUTYRIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-CHLOROBUTYRIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-CHLOROBUTYRIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-CHLOROBUTYRIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used in Grignard reactions and esterification |
| Pesticides | Preparation of herbicide intermediates | Applied in chlorination and acylation |
| Chemicals | Production of specialty chemicals | Employed in hydroxylation and substitution reactions |
Manufacturing Quality Control of 4-CHLOROBUTYRIC ACID
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and a UV detector (approximately 210 nm), with a mobile phase system consisting of water-organic solvent (e.g., methanol or acetonitrile) containing buffer salts (e.g., phosphate) for gradient or isocratic elution to quantitatively analyze the content of 4-chloropropionic acid. This method is sensitive and accurate, suitable for purity and assay analysis. |
| Purity and Impurity Analysis | Gas Chromatography (GC) | After derivatization (e.g., esterification to form methyl or ethyl esters), separation is performed using a capillary gas chromatography column with FID detection. Suitable for analyzing volatile and semi-volatile impurities, this method can assess sample purity. |
| Structural Confirmation | Infrared Spectroscopy (IR) | Analyzes characteristic absorption peaks of functional groups in the infrared spectrum, such as the strong carboxyl (—COOH) absorption peak near 1700 cm⁻¹ and the C—Cl bond stretching vibration peak in the 600–800 cm⁻¹ range, to confirm molecular structure. |
| Residual Solvent Testing | Headspace-Gas Chromatography (HS-GC) | Employs headspace sampling combined with gas chromatography-FID detection to identify residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) possibly remaining from manufacturing processes, complying with pharmacopoeial requirements for residual solvent control. |
| Moisture Content | Karl Fischer Titration | Determines moisture content in samples by measuring the quantitative reaction of iodine and sulfur dioxide with water in an anhydrous environment, via volumetric titration or coulometric methods; suitable for trace moisture determination. |
| Acid Value / Titration Purity | Acid-Base Titration | Titrates the carboxylic group of 4-chloropropionic acid with a standard sodium hydroxide solution, using phenolphthalein or potentiometric endpoint detection to calculate acid value or equivalent concentration, providing a rapid assessment of acidity strength and approximate purity. |
| Heavy Metal Residue | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, heavy metal residues (e.g., lead, cadmium, mercury, arsenic) are measured using atomic absorption spectroscopy or inductively coupled plasma mass spectrometry to ensure compliance with safety limits. |
| Related Substances (Isomers) | HPLC or GC | Uses chromatographic methods to separate and detect potential isomeric impurities (e.g., 2-chloropropionic acid, 3-chloropropionic acid), evaluating by-product control in selective synthesis processes. |
Technical Specifications of 4-CHLOROBUTYRIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 220-235 mg KOH/g |
| Refractive Index (n20/D) | 1.442-1.446 |
| Relative Density (20°C/25°C) | 1.205-1.215 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-CHLOROBUTYRIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-CHLOROBUTYRIC ACID
Packaging of 4-CHLOROBUTYRIC ACID
Industrial 4-CHLOROBUTYRIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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