D-(-)-Arginine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 627-75-8 |
| Product name | D-(-)-Arginine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-(-)-Arginine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-(-)-Arginine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-(-)-Arginine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Component of amino acid infusion solutions, nutritional supplement, and adjuvant therapy for hepatic encephalopathy | Formulated as an active pharmaceutical ingredient into intravenous infusions or oral dosage forms via sterile preparation or solid-dosage manufacturing processes |
| Pharmaceuticals | Chiral drug synthesis intermediate | Used in resolution or asymmetric synthesis of chiral drugs such as L-arginine derivatives and angiotensin-converting enzyme (ACE) inhibitors |
| Food | Food additive (nutritional fortifier) | Added to special dietary foods and sports nutrition products per GB 2760, incorporated via food processing operations including blending, homogenization, and drying |
| Cosmetics | Skin-conditioning agent and humectant | Incorporated into skincare formulations such as emulsions and serums via cosmetic manufacturing processes including emulsification, homogenization, and filling |
| Life Sciences Research | Cell culture medium component | Supplemented as an essential amino acid into culture media such as DMEM and RPMI-1640, followed by sterile filtration and aseptic dispensing |
Manufacturing Quality Control of D-(-)-Arginine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Arginine HCl content) | Acid-base titration with NaOH | Quantitative neutralization of hydrochloride salt using standardized sodium hydroxide solution, with methyl red indicator. |
| Specific Optical Rotation | [alpha]D | Measurement of optical rotation at 589 nm using a polarimeter to confirm chiral purity and identity. |
| Water Content | Karl Fischer titration | Electrochemical titration using iodine, sulfur dioxide, and pyridine-based reagent to determine trace water. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantification of Pb, Cd, Hg, As, and other heavy metals after acid digestion and flame or graphite furnace atomization. |
| Chloride Impurity | Potentiometric titration with AgNO3 | Titration with silver nitrate using a silver electrode to detect chloride ion concentration. |
| Residue on Ignition | Gravimetric analysis | Weighing residue remaining after high-temperature ashing to assess inorganic impurities. |
| pH of Aqueous Solution | pH meter measurement | Direct potentiometric measurement of pH in a defined aqueous solution (e.g., 1% w/v). |
| Related Substances | Reverse-phase HPLC with UV detection | Separation and quantification of structurally related amino acids and degradation products using C18 column and UV detection at 200 nm. |
| Microbial Contamination | Membrane filtration followed by colony counting | Enumeration of aerobic bacteria, yeasts, and molds via filtration, incubation on appropriate agar media, and CFU enumeration. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against standard reference under controlled lighting. |
| Solubility | Qualitative dissolution test | Observation of complete dissolution in specified solvents (e.g., water, methanol) within defined time and temperature conditions. |
| Loss on Drying | Thermogravimetric analysis (TGA) or oven drying | Weight loss measured after heating at 105 C for specified duration to determine volatile components. |
Technical Specifications of D-(-)-Arginine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to pale cream powder |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 223-227°C (decomposes) |
| Optical Rotation | -21.0° to -20.0° (c=1, 1M HCl) |
| Total Impurities | <=2.0% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-(-)-Arginine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-(-)-Arginine hydrochloride
Packaging of D-(-)-Arginine hydrochloride
Industrial D-(-)-Arginine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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