1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62780-89-6 |
| Product name | 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key Intermediate | Used in the synthesis of the antiemetic drug domperidone via N-alkylation to generate the intermediate 5-chloro-1-[1-[3-(2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. |
| Pharmaceutical Chemicals | R&D Building Block | Serves as a structural unit for benzimidazolone derivatives, enabling construction of compound libraries with potential biological activity for drug screening and new drug development. |
| Organic Synthesis | Alkylation Reagent | Acts as an electrophile via its 3-chloropropyl side chain, undergoing nucleophilic substitution with piperidine derivatives or other nitrogen-containing heterocycles under basic conditions to form C–N bonds. |
Manufacturing Quality Control of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and form (e.g., white to pale crystalline powder) of the sample to determine whether it conforms to the standard description. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column to separate the main component with an appropriate mobile phase (e.g., methanol/buffer system). Quantify the purity of the main component using area normalization or external standard method. |
| Related Substances (Impurities) | HPLC (Gradient Elution) | Separate potential process impurities and degradation products using a gradient elution program. Set the detection wavelength (e.g., 254 nm), and calculate impurity content by self-reference method or area normalization. |
| Drying Loss | Drying Method (105°C, constant weight) | Dry the sample at 105°C until constant weight, and measure the percentage of mass loss to evaluate the moisture and volatile substance content. |
| Melting Point | Capillary Melting Point Determination | Determine the initial and final melting temperatures using a digital melting point apparatus, and assess whether the physical constants fall within the specified range. |
| Residual Solvents | Gas Chromatography (GC-FID/HS-GC) | Use headspace or direct injection, and separate residual organic solvents (e.g., methanol, ethyl acetate) using a polar or non-polar capillary column with FID detector for quantification. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine the residual levels of heavy metals such as lead, arsenic, cadmium, and mercury to ensure compliance with pharmacopoeia or ICH Q3D limits. |
| pH Value (Solution) | pH Meter Measurement | Prepare a solution of a certain concentration (e.g., 1% w/v), calibrate the pH meter, and measure the pH value to assess the effect of acidity or alkalinity on stability. |
| Content Determination | HPLC External Standard Method | Compare the response value of the main peak with a reference standard of known purity under the same chromatographic conditions to calculate the content of the target compound in the sample. |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric KF titration to accurately determine the water content in the sample, suitable for compounds sensitive to moisture. |
Technical Specifications of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142–146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
Industrial 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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