China Factory Direct
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| CAS number | 628-20-6 |
| Product name | 4-Chlorobutyronitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pesticides | Intermediate for synthesizing insecticides and herbicides | Used to prepare nitrogen-, oxygen-, or sulfur-containing pesticide active ingredients via nucleophilic substitution of 4-chlorobutyronitrile with amines, alcohols, or thiols |
| Pharmaceuticals | Precursor for antiviral drugs and neuroactive compounds | Applied as an intermediate bearing both cyano and chloroalkyl functionalities, participating in cyclization, reduction, or coupling reactions to generate drug molecules |
| Organic Synthesis | Preparation of cyanide-containing heterocyclic compounds and functional materials | Employed in Staudinger reactions, Darzens reactions, or reactions with organometallic reagents to introduce the 4-chlorobutyl cyano structural motif |
| Dyes | Intermediate for synthesizing dyes with specialized structures | Utilized to generate carboxylic acid or amide derivatives via hydrolysis or ammonolysis of the cyano group, supporting molecular design of azo and anthraquinone dyes |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of suspended particles or precipitates under natural light or standard illumination. |
| Content (Purity) | Gas Chromatography (GC) | Use a capillary gas chromatograph to quantify 4-chlorobutyronitrile by comparing retention times and peak areas with reference standards; a flame ionization detector (FID) is commonly used. |
| Water Content | Karl Fischer Titration | Determine water content using electrochemical titration principles; suitable for trace water detection with high accuracy and ease of operation. |
| Acid Value (Acidity) | Acid-Base Titration | Dissolve the sample in an appropriate solvent (e.g., ethanol) and titrate free acids with a standardized sodium hydroxide solution; calculate acid value (expressed as HCl or mg KOH/g). |
| Cyanide Impurities | Spectrophotometry or Ion Chromatography | After hydrolysis or derivatization, detect free cyanide ions; spectrophotometry relies on the Prussian blue reaction, while ion chromatography enables direct quantification of cyanide ions. |
| Chloride Content | Ion Chromatography or Argentometric Titration | Ion chromatography precisely measures inorganic chloride ions; argentometric titration using silver nitrate is suitable for detecting higher concentrations of chlorides. |
| Organic Impurities (By-products) | High-Performance Liquid Chromatography (HPLC) or GC-MS | HPLC is used for analysis of polar impurities; GC-MS combined with mass spectrometry enables qualitative and quantitative identification of unknown impurities (e.g., alcohols, aldehydes, esters) formed during synthesis. |
| Density | Pycnometer Method or Digital Density Meter | Measure mass per unit volume at a specified temperature (e.g., 20°C) to verify consistency of the substance. |
| Refractive Index | Refractometry | Use an Abbe refractometer to measure refractive index at a standard temperature; serves as an auxiliary indicator for identification and purity assessment. |
| Boiling Point / Distillation Range | Distillation Method | Determine initial and final boiling points to evaluate volatility and compositional uniformity; suitable for batch-to-batch consistency verification of raw materials. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.435–1.445 |
| Relative Density (20°C/25°C) | 1.120–1.140 g/cm³ |
| Odor | Characteristic pungent odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.