5-BROMO-2-FLUOROPYRIMIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 62802-38-4 |
| Product name | 5-BROMO-2-FLUOROPYRIMIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-BROMO-2-FLUOROPYRIMIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-BROMO-2-FLUOROPYRIMIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-BROMO-2-FLUOROPYRIMIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key Intermediate | Used in the synthesis of tyrosine kinase inhibitors (e.g., gefitinib, erlotinib) and nonsteroidal anti-inflammatory drugs as a pyrimidine ring building block |
| Agrochemicals | Core Raw Material | Applied in the synthesis of pyrimidine-based fungicides and herbicides to enhance biological activity via pyrimidine ring incorporation |
| Organic Synthesis | Substrate for Nucleophilic Substitution Reactions | Leverages the reactivity of bromine to undergo palladium-catalyzed coupling reactions (e.g., Suzuki, Stille) for constructing complex aryl derivatives |
| Organic Synthesis | Reagent for Functionalization | Enables nucleophilic aromatic substitution (SNAr) via fluorine’s specificity to prepare amino- or alkoxy-substituted fluoropyrimidine derivatives |
Manufacturing Quality Control of 5-BROMO-2-FLUOROPYRIMIDINE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Measuring the infrared absorption spectrum of the sample and comparing it with the standard spectrum to confirm the characteristic functional groups and structure of 5-bromo-2-fluoropyrimidine. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column, with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (typically at around 254 nm) for detection. The content of the main component is calculated using an external standard method. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Similar conditions to content determination, but with optimized gradient elution programs to separate potential impurities (such as starting materials, intermediates, by-products, etc.). Quantitative analysis is performed using area normalization or the main component self-reference method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection, using a polar or non-polar capillary column, and a FID detector. It is used to perform qualitative and quantitative analysis of possible residual organic solvents (such as dichloromethane, methanol, ethanol, etc.) according to the Chinese Pharmacopoeia or ICH guidelines. |
| Moisture | Karl Fischer Titration | Determining the moisture content of the sample using volumetric or coulometric methods, suitable for quality control of moisture-sensitive organic compounds. |
| Melting Point | Capillary Melting Point Method | Fill the sample into a melting point capillary and slowly heat it in a melting point apparatus. Observe and record the initial and final melting temperatures, and compare them with the standard value to assess purity. |
| Appearance and Physical Characteristics | Visual Inspection | Observe the color and state (e.g., white to off-white crystalline powder) of the sample under natural light or standard lighting to ensure it meets the specified requirements. |
Technical Specifications of 5-BROMO-2-FLUOROPYRIMIDINE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 78–82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-BROMO-2-FLUOROPYRIMIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-BROMO-2-FLUOROPYRIMIDINE
Packaging of 5-BROMO-2-FLUOROPYRIMIDINE
Industrial 5-BROMO-2-FLUOROPYRIMIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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