3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6283-81-4 |
| Product name | 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of anticancer agents (e.g., nilotinib) | Used to construct the pyridopyrimidine core structure via condensation and cyclization reactions with aryl amines or heterocyclic compounds |
| Pharmaceuticals | Synthesis of kinase inhibitor drugs | Participates in multistep organic synthesis, including nucleophilic substitution, reduction, and coupling reactions |
| Pesticides | Synthetic precursor for certain insecticides or herbicides | Processed into active ingredients via ester hydrolysis, amidation, or further functional group transformations |
| Chemical Research | Synthetic building block for constructing pyridine-containing heterocyclic compounds | Applied in classical organic reactions such as Knoevenagel condensation and Michael addition in laboratory settings |
Manufacturing Quality Control of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area to calibrated standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separates and detects structurally related impurities (e.g., unreacted 3-pyridylacetone, hydrolysis products) via chromatographic resolution and spectral identification. |
| Residual Solvents (Ethanol, Ethyl Acetate) | GC-FID | Quantifies volatile organic solvents by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water via electrochemical iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein) | Measures free carboxylic acid groups (e.g., from hydrolysis) by titration with standardized sodium hydroxide solution. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Quantifies trace metallic impurities after acid digestion using inductively coupled plasma mass spectrometry for multi-element ultra-trace detection. |
| Optical Rotation | [α]D | Measures specific rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity and absence of racemization. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual non-volatile matter. |
| Melting Point | Capillary Melting Point Apparatus | Determines thermal transition range using calibrated capillary apparatus per pharmacopeial standards (e.g., USP <741>). |
Technical Specifications of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
| Color (APHA/Pt-Co) | <=100 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
Safety Information of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER
Industrial 3-OXO-3-PYRIDIN-3-YL-PROPIONIC ACID ETHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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