China Factory Direct
|
|
| CAS number | 63069-50-1 |
| Product name | 3-Fluoro-4-aminobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of fluorinated pesticide intermediates | Used as a key intermediate in aromatic ring substitution reactions to prepare insecticides such as fipronil and flumetramide |
| Pharmaceuticals | Synthesis of antitumor and central nervous system drugs | Applied as a benzonitrile structural unit in nucleophilic substitution or coupling reactions to construct drug molecule scaffolds |
| Dyes and Pigments | Synthesis of high-performance organic pigments | Applied as an aromatic nitrile derivative in condensation or diazotization reactions to produce light- and weather-resistant dyes |
| Electronic Materials | Preparation of liquid crystal display material intermediates | Modified via functional group reactions between the cyano and amino groups to synthesize fluorinated liquid crystal compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., 3-fluoro-4-cyanoaniline, residual starting materials) via gradient HPLC/UV or high-resolution UPLC-MS. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., DMF, THF, methanol) based on calibrated external standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, using isotopic detection for sub-ppb sensitivity and compliance with ICH Q3D limits. |
| Chloride Ion Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on a high-capacity anion-exchange column; chloride quantified by conductivity response relative to calibration standards. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically during controlled heating; used for identity confirmation and purity screening per USP <741>. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after controlled ashing at 700–800 °C, indicating inorganic salt contaminants. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective assessment of crystalline form and color intensity compared to standardized platinum-cobalt (APHA) solutions per USP <631>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.