BOC-LEU-OME Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 63096-02-6 |
| Product name | BOC-LEU-OME |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for BOC-LEU-OME
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-LEU-OME Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-LEU-OME
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral building block for peptide-based drug synthesis, used in the preparation of anticancer, antiviral, and metabolic disease therapeutics | Leucine derivative employed as an N-terminal protecting group in solid-phase peptide synthesis (SPPS) or solution-phase peptide synthesis; peptide chain elongation proceeds after BOC deprotection and coupling |
| Pharmaceutical Intermediates | Key chiral intermediate for synthesizing protease inhibitors (e.g., HIV protease inhibitors) and GLP-1 receptor agonists (e.g., semaglutide analogues) | Multi-step organic transformations—including selective methyl ester hydrolysis, amidation, and cyclization—to construct the core structure of the active molecule |
| Biochemical Research | Standard reagent for peptide structure–activity relationship (SAR) studies and enzyme substrate specificity analysis | Used as a model substrate in in vitro enzymatic reaction systems to evaluate the catalytic activity and stereoselectivity of proteases, esterases, or aminopeptidases |
Manufacturing Quality Control of BOC-LEU-OME
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies BOC-L-leucine methyl ester by separation on a reversed-phase column and UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Resolves enantiomers using a chiral stationary phase; L-isomer content is determined by comparing retention times and peak areas relative to an L-enantiomer reference. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-methanol solvent system. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, dichloromethane) by gas chromatographic separation and flame ionization detection. |
| Heavy Metals | ICP-OES | Determines total elemental impurities (e.g., Pb, Cd, Ni) after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection, calibrated against sodium chloride standards. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion with sulfuric acid treatment and high-temperature incineration, followed by weighing of the residual ash. |
| Optical Rotation | Polarimetry | Measures specific rotation using plane-polarized light; deviation angle correlates with enantiomeric excess and concentration in solution. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against established visual standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity based on sharpness and agreement with literature value. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., BOC-L-leucine, de-BOC product) using gradient elution and UV detection. |
| Residual Palladium | ICP-MS | Quantifies trace palladium from catalytic hydrogenation steps via mass spectrometric detection of Pd isotopes after microwave-assisted digestion. |
Technical Specifications of BOC-LEU-OME
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62-66°C |
| Optical Rotation | +11.0° to +13.0° (c=1, in CHCl3) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of BOC-LEU-OME
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-LEU-OME
Packaging of BOC-LEU-OME
Industrial BOC-LEU-OME Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply