5-tert-butoxy-5-oxopentanoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 63128-51-8 |
| Product name | 5-tert-butoxy-5-oxopentanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-tert-butoxy-5-oxopentanoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-tert-butoxy-5-oxopentanoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-tert-butoxy-5-oxopentanoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used to synthesize drug molecules containing the glutaric acid motif, such as protease inhibitors and targeted protein degraders (PROTACs) | Under inert atmosphere, undergoes condensation with amines, followed by deprotection (e.g., with trifluoroacetic acid) to yield the free carboxylic acid product |
| Organic Synthesis | Serves as a selectively mono-protected glutaric acid derivative for constructing asymmetric molecules or complex natural product fragments | Additional functional groups are introduced via transesterification or acyl chloride formation–alcoholysis; the tert-butyl ester group provides site-selective protection, enabling subsequent regioselective modification |
| Materials Science | Used as a precursor for degradable polyesters or functionalized comonomers | Reacted with diols (e.g., ethylene glycol, 1,4-butanediol) via melt or solution polycondensation to generate prepolymers bearing tert-butyl ester side chains, followed by acid-catalyzed deprotection and crosslinking to tailor material properties |
Manufacturing Quality Control of 5-tert-butoxy-5-oxopentanoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., di-tert-butyl ester, unreacted acid) using gradient HPLC and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, isopropanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups by titration with standardized KOH solution in ethanol/isopropanol mixture. |
| Color | APHA Color Scale | Evaluates visual color intensity by comparison to platinum-cobalt standard solutions using a Nessler tube or spectrophotometer. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weighing of residual residue. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to assess chiral purity; compound is typically achiral but method verifies absence of optically active contaminants. |
| Bulk Density | ASTM D1895 | Determines mass per unit volume of freely settled powder using standardized graduated cylinder and balance per ASTM method. |
Technical Specifications of 5-tert-butoxy-5-oxopentanoic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 150–165 mg KOH/g |
| Odor | Characteristic ester-like odor |
| Solubility | Soluble in common organic solvents (e.g., ethanol, acetone, ethyl acetate); insoluble in water |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-tert-butoxy-5-oxopentanoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-tert-butoxy-5-oxopentanoic acid
Safety Information of 5-tert-butoxy-5-oxopentanoic acid
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-tert-butoxy-5-oxopentanoic acid
Industrial 5-tert-butoxy-5-oxopentanoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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