China Factory Direct
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| CAS number | 632-20-2 |
| Product name | D-Threonine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Food Industry | Nutritional fortificant; used to supplement essential amino acids in functional foods, beverages, and infant formula | D-Threonine produced via fermentation or chemical synthesis, then purified and incorporated into food products |
| Feed Additives | Amino acid supplement in animal feed to enhance growth performance and feed conversion efficiency in poultry and swine | Large-scale production via microbial fermentation, followed by spray drying or granulation to formulate feed additives |
| Pharmaceutical Industry | Intermediate for drug synthesis, including antiviral agents, antibiotics, and metabolic therapeutics | Chiral synthesis using asymmetric synthesis or enzymatic catalysis to construct specific molecular structures |
| Biotechnology | Model amino acid in biosynthesis research, applied in protein engineering and metabolic pathway modification | High-yield production achieved by overexpressing threonine biosynthesis-related genes in genetically engineered strains (e.g., Escherichia coli) during fermentation |
| Chemical Reagents | Chiral synthesis reagent or reference standard for laboratory research | High-purity product obtained via high-performance liquid chromatography (HPLC) purification to meet research requirements |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Threonine Content) | Acid-Base Titration with HCl | Quantifies D-threonine by titration with standardized hydrochloric acid using bromocresol green indicator. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 20 C using sodium D-line (589 nm) to confirm chiral purity and identity. |
| Loss on Drying | Gravimetric Method (105 C, 2 h) | Determines volatile content by weight loss after drying under controlled temperature and time. |
| Residue on Ignition | Gravimetric Ashing (500-600 C) | Measures inorganic impurities as non-volatile residue after high-temperature ignition. |
| Chloride Impurity | Argentometric Titration (Mohr Method) | Quantifies chloride ions by precipitation titration with silver nitrate using potassium chromate indicator. |
| Sulfate Impurity | Barium Sulfate Gravimetric Method | Precipitates sulfate as BaSO4 and determines mass gravimetrically after filtration and drying. |
| Heavy Metals (as Pb) | Colorimetric Limit Test with Thioglycollic Acid | Forms colored metal-thioglycolate complexes under buffered conditions; compared visually to lead standard. |
| Iron Impurity | UV-Vis Spectrophotometry (1,10-Phenanthroline) | Forms orange-red Fe(II)-phenanthroline complex; absorbance measured at ~510 nm. |
| Related Substances | HPLC with UV Detection | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV detection at 200-220 nm. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemically determines water content via iodine generation and stoichiometric reaction with water. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in 1% w/v aqueous solution using calibrated glass electrode. |
| Microbial Contamination | Membrane Filtration and Plate Count | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-255°C (dec.) |
| Optical Rotation | +27.0 to +29.0° (c=1, H2O) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.