1-hydroxy-1H-benzotriazole, ammonium salt Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 63307-62-0 |
| Product name | 1-hydroxy-1H-benzotriazole, ammonium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-hydroxy-1H-benzotriazole, ammonium salt
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-hydroxy-1H-benzotriazole, ammonium salt Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-hydroxy-1H-benzotriazole, ammonium salt
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Coupling agent additive in peptide synthesis | Used as the ammonium salt form of HOBT (hydroxybenzotriazole) in solid-phase or solution-phase peptide synthesis to activate carboxylic acids and facilitate amide bond formation while minimizing racemization |
| Biochemistry | Additive for coupling reactions | Used in combination with carbodiimide reagents (e.g., EDC or DCC) to enhance efficiency and selectivity in protein, peptide, and small-molecule coupling reactions |
| Fine Chemicals | Intermediate protection and activation | Applied as a temporary protecting/activating group in complex organic molecule synthesis to improve reaction yield and product purity |
Manufacturing Quality Control of 1-hydroxy-1H-benzotriazole, ammonium salt
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (HOBT ammonium salt content) | Acid-base titration | Quantifies active ingredient by titration with standardized HCl solution using bromocresol green indicator. |
| Water content | Karl Fischer titration | Measures water via coulometric or volumetric reaction between water and iodine in pyridine/methanol medium. |
| Residual solvents (e.g., THF, DMF) | Gas chromatography (GC-FID) | Separates and quantifies volatile organic solvents using flame ionization detection. |
| Heavy metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metal impurities by ionizing sample in plasma and measuring mass-to-charge ratios. |
| Chloride ion | Ion chromatography (IC) | Separates and quantifies chloride anions using suppressed conductivity detection. |
| Sulfate ion | Ion chromatography (IC) | Separates and quantifies sulfate anions using suppressed conductivity detection. |
| pH of aqueous solution | pH meter measurement | Determines acidity/basicity of a defined aqueous suspension using calibrated glass electrode. |
| Appearance (color and clarity) | Visual inspection | Evaluates physical state against standard reference under controlled lighting and white background. |
| Particle size distribution | Laser diffraction | Measures particle size by analyzing angular scattering pattern of laser beam passing through dispersed sample. |
| Loss on drying (LOD) | Gravimetric analysis | Determines volatile content by weight loss after heating at specified temperature and time. |
| Related substances (impurity profiling) | HPLC-UV | Separates and quantifies structural analogs and degradation products using reversed-phase column and UV detection. |
| Residual catalyst (e.g., Pd) | ICP-OES | Quantifies palladium and other metallic catalyst residues by optical emission from excited plasma atoms. |
Technical Specifications of 1-hydroxy-1H-benzotriazole, ammonium salt
| Test Item | Specification |
|---|---|
| Appearance | Yellow powder |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.3% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-hydroxy-1H-benzotriazole, ammonium salt
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-hydroxy-1H-benzotriazole, ammonium salt
Safety Information of 1-hydroxy-1H-benzotriazole, ammonium salt
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-hydroxy-1H-benzotriazole, ammonium salt
Industrial 1-hydroxy-1H-benzotriazole, ammonium salt Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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