China Factory Direct
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| CAS number | 6331-09-5 |
| Product name | H-D-ALA-OET HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of antibiotics and peptide-based drugs | Used as a chiral building block in the construction of β-lactam antibiotics or bioactive peptides |
| Biochemical Research | Preparation of amino acid derivatives | Applied to modify amino acid structures for studying enzyme-catalyzed reactions or metabolic pathways |
| Pesticide Synthesis | Chiral pesticide intermediates | Employed in synthesizing chiral pesticide molecules containing an alanine moiety to enhance selectivity and biological activity |
| Organic Synthesis | Chiral auxiliaries or protecting group carriers | Leverages its ester and amino hydrochloride functionalities to enable functional group protection and stereochemical control in multistep syntheses |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Alanine Ethyl Ester Hydrochloride) | Acid-Base Titration with NaOH | Quantifies active compound by neutralizing HCl salt with standardized NaOH using phenolphthalein or potentiometric endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Determines enantiomeric purity by measuring rotation of plane-polarized light at 20 C and 589 nm using a calibrated polarimeter. |
| Water Content | Karl Fischer Titration | Measures trace water via stoichiometric iodine reaction with sulfur dioxide and methanol in pyridine-free reagent system. |
| Residual Solvents (Ethanol, Ethyl Acetate) | Gas Chromatography (GC) with FID | Separates and quantifies volatile solvents using capillary column and flame ionization detection against external standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Quantifies trace metals after acid digestion by measuring elemental mass-to-charge ratios with high sensitivity and multi-element capability. |
| Chloride Impurity | Potentiometric Titration with AgNO3 | Detects chloride ions by titration with silver nitrate using silver indicator electrode and reference electrode. |
| Related Substances (Impurity Profile) | HPLC with UV Detection | Separates and quantifies structurally related impurities (e.g., D-alanine, ethyl ester hydrolysis products) on reversed-phase C18 column at 210 nm. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Determines acidity/basicity of aqueous solution using calibrated glass electrode pH meter at 25 C. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against standard white background under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated digital melting point instrument. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 700-800 C and subsequent weighing. |
| Microbial Contamination | Membrane Filtration and Plate Count | Quantifies aerobic microorganisms by filtration, membrane transfer to soybean-casein digest agar, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | -2.8 to -2.4 (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.