China Factory Direct
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| CAS number | 6332-56-5 |
| Product name | 3-Nitro-2-pyridinol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used to prepare azaindole derivatives |
| Agrochemicals | Preparation of active pharmaceutical ingredients (APIs) | Serves as a synthetic precursor for nitrogen-containing heterocyclic compounds |
| Dyes | Production of acid dyes | Participates in heterocyclic structure construction reactions |
| Analytical Chemistry | Used as an analytical reagent | Participates in colorimetric or derivatization reactions in specific analytical methods |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection | Observe the sample's color, physical state (e.g., powder, crystal), presence of lumping or visible impurities. Typically, it should appear as a pale yellow to yellow crystalline powder. |
| Purity and Main Component Content | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of methanol-water or acetonitrile-water (containing buffer salts such as phosphate). Detect at UV wavelengths between 254–310 nm using a UV detector. Calculate purity and content of the main peak via external standard method or normalization method. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilize ¹H-NMR and ¹³C-NMR to confirm the molecular structure by comparing chemical shifts of hydroxyl groups, nitro groups, and hydrogen/carbons on the pyridine ring with published literature data. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Detect characteristic functional group absorption peaks: e.g., O-H stretching vibration (~3200–3500 cm⁻¹), asymmetric NO₂ stretching (~1530 cm⁻¹), and aromatic C=C skeletal vibrations (~1600, 1500 cm⁻¹). |
| Moisture Content | Karl Fischer Titration | Quantitatively determine water content based on the reaction between iodine and sulfur dioxide in an anhydrous environment. Suitable for trace moisture analysis. |
| Residual Solvents | Gas Chromatography (GC) | Follow ICH guidelines to detect organic solvents potentially remaining from production processes (e.g., methanol, ethanol, acetone, dichloromethane). Use polar or non-polar capillary columns for separation and FID detection. |
| Melting Point | Melting Point Apparatus Method | Determine initial and final melting temperatures using automatic or manual melting point apparatus, used to assess substance purity and consistency. |
| Related Substances (Impurities) | HPLC (Gradient Elution) | Optimize gradient elution program to separate the main component from potential synthesis intermediates or degradation products. Calculate areas of impurity peaks and report their relative percentages. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, detect residual heavy metals such as lead, cadmium, mercury, and arsenic. Results must comply with pharmacopoeial or relevant safety standards. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | Incinerate the sample at high temperature, then treat with sulfuric acid, followed by weighing the residual inorganic matter to assess inorganic impurity levels. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 78-82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.