D-Histidine hydrochloride monohydrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6341-24-8 |
| Product name | D-Histidine hydrochloride monohydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Histidine hydrochloride monohydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Histidine hydrochloride monohydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Histidine hydrochloride monohydrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral resolution or identification of chiral compounds (e.g., as chiral stationary phases or chiral additives) | Liquid chromatography or capillary electrophoresis analysis |
| Pharmaceutical Industry | Use as a selective local vasodilator or adjunct diagnostic agent (histamine-releasing agent) | Enzyme-linked immunosorbent assay (ELISA) or in vivo stimulation testing |
| Chemical Research | Organic synthesis intermediate or chiral building block | Chemical synthesis reactions |
| Biological Research | Receptor function studies and pharmacological analysis | In vitro receptor binding assays |
Manufacturing Quality Control of D-Histidine hydrochloride monohydrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Histamine HCl monohydrate content) | Acid-base titration with standardized NaOH | Neutralization of the hydrochloride salt in aqueous solution using phenolphthalein or potentiometric endpoint detection. |
| Water content | Karl Fischer titration | Quantitative determination of water based on iodine-sulfur dioxide reaction in methanol/pyridine medium. |
| Residual solvents | Gas chromatography (GC) with FID | Separation and quantification of volatile organic solvents using capillary column and flame ionization detection. |
| Heavy metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection of trace metals after acid digestion by inductively coupled plasma mass spectrometry. |
| Chloride impurity | Potentiometric titration with AgNO3 | Precipitation titration using silver nitrate and silver electrode for endpoint detection. |
| Related substances | HPLC with UV detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and UV absorbance at 210 nm. |
| Optical rotation | [alpha]D measurement | Determination of specific optical rotation using sodium D-line light source to confirm chiral purity and identity. |
| pH of aqueous solution | pH meter measurement | Direct measurement of hydrogen ion activity in a defined concentration (e.g., 1% w/v) aqueous solution at 25 degC. |
| Sulfated ash | Gravimetric analysis | Ignition of sample at 600-700 degC followed by weighing of non-volatile inorganic residue. |
| Particle size distribution | Laser diffraction | Analysis of scattered laser light intensity to determine volume-based particle size distribution in dispersed suspension. |
| Microbial limits | Membrane filtration and plate count | Enumeration of aerobic mesophilic bacteria and fungi after filtration and incubation on appropriate agar media. |
| Residue on ignition | Gravimetric analysis | Weight loss upon high-temperature ignition reflects volatile and organic content; residue weight indicates inorganic impurities. |
Technical Specifications of D-Histidine hydrochloride monohydrate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline powder |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-214°C (decomposes) |
| Optical Rotation | -10.0 to -11.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Histidine hydrochloride monohydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Histidine hydrochloride monohydrate
Safety Information of D-Histidine hydrochloride monohydrate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of D-Histidine hydrochloride monohydrate
Industrial D-Histidine hydrochloride monohydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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