N-Benzylglycine ethyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6344-42-9 |
| Product name | N-Benzylglycine ethyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Benzylglycine ethyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Benzylglycine ethyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Benzylglycine ethyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antihypertensive drug telmisartan | Undergoes asymmetric alkylation with a chiral catalyst under basic conditions, followed by hydrolysis and cyclization to form the telmisartan core structure |
| Pharmaceutical Intermediates | Building block for the side chain of β-lactam antibiotics (e.g., certain carbapenem derivatives) | After conversion to the corresponding acyl chloride, undergoes condensation with the β-lactam nucleus to introduce the N-benzylglycine ethyl ester-derived side chain |
| Organic Synthesis | Chiral auxiliary or amino-protecting/activating reagent in phase-transfer catalysis | Deprotonation to generate a nitrogen anion in the presence of a strong base (e.g., NaH), enabling C–N bond formation via alkylation or Michael addition; the benzyl group is removable by hydrogenolysis, and the ethyl ester is selectively hydrolysable or ammonolyzable |
| Pesticide Development | Synthesis of novel plant growth regulators or fungicidal lead compounds containing a glycine backbone | Multi-step functionalization—including reductive amination and heterocyclic coupling—to construct libraries of biologically active N-benzylglycine derivatives |
Manufacturing Quality Control of N-Benzylglycine ethyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold limits. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content by stoichiometric reaction with iodine and sulfur dioxide. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual ethyl acetate, ethanol, or toluene against calibrated standards. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on change in potential due to AgCl precipitation. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectrometry based on element-specific emission wavelengths. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Direct measurement of hydrogen ion activity in a freshly prepared aqueous solution using a calibrated glass electrode pH meter. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against defined standards under controlled white light and against a white background. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light through a solution, indicating chiral purity and identity via comparison to literature values. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (600-800 C) to determine inorganic ash content. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens using membrane filtration followed by incubation on appropriate agar media. |
Technical Specifications of N-Benzylglycine ethyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Benzylglycine ethyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Benzylglycine ethyl ester hydrochloride
Safety Information of N-Benzylglycine ethyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Benzylglycine ethyl ester hydrochloride
Industrial N-Benzylglycine ethyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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