China Factory Direct
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| CAS number | 63463-36-5 |
| Product name | 1-Methylpiperdin-4-ylmagnesium chloride, 0.50 M in THF |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates Synthesis | Used to synthesize piperidine-containing drug molecules, such as antipsychotics and analgesics | Participates in nucleophilic addition or substitution reactions to construct C–C bonds or introduce methylpiperidinyl groups |
| Organic Synthesis Reagent | Acts as a Grignard reagent for constructing complex organic molecular frameworks | Undergoes coupling reactions with carbonyl compounds, alkyl halides, and other substrates under anhydrous and oxygen-free conditions |
| Pesticide Development | Synthesizes novel nitrogen-containing heterocyclic pesticide active ingredients | Introduces the 1-methylpiperidin-4-yl functional group via Grignard reaction to optimize biological activity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (main component content) | Gas Chromatography (GC) with FID detection | Quantifies 1-methylpiperidin-4-ylmagnesium chloride by retention time and peak area against a calibrated standard, assuming stable derivatization or direct analysis under inert conditions. |
| Residual Solvents (THF, diethyl ether) | Gas Chromatography (GC) with headspace sampling | Separates and quantifies volatile solvents based on partitioning into headspace gas phase and thermal conductivity or FID response. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between water, iodine, sulfur dioxide, and base in methanol/pyridine medium. |
| Magnesium Content | Complexometric Titration with EDTA | Determines Mg2+ concentration by chelation with standardized EDTA solution using Eriochrome Black T indicator. |
| Chloride Ion Content | Potentiometric Titration with AgNO3 | Quantifies Cl- by precipitation titration using silver nitrate and a silver indicator electrode. |
| Heavy Metals (Pb, Cd, Ni, Fe) | ICP-OES | Simultaneously detects trace metal impurities after acid digestion by measuring element-specific atomic emission intensities in plasma. |
| Residual Alkyl Halides (e.g., chloromethane, 1-chloro-4-methylpiperidine) | Gas Chromatography-Mass Spectrometry (GC-MS) | Identifies and quantifies organic impurities by retention time and characteristic mass fragmentation patterns. |
| pH of Aqueous Hydrolysate | pH Meter Measurement | Evaluates acidity/basicity after controlled hydrolysis to assess residual acidic or basic impurities. |
| Appearance and Color | Visual Inspection Against Standard | Assesses physical state, clarity, and color deviation from reference samples under controlled lighting. |
| Density | Digital Density Meter | Determines mass per unit volume at specified temperature using oscillating U-tube principle. |
| Viscosity | Rotational Viscometer | Measures resistance to flow under defined shear rate and temperature using spindle rotation in sample. |
| Stability Indicating Impurities (degradation products) | High Performance Liquid Chromatography (HPLC) with UV detection | Separates and quantifies structurally related degradants using reversed-phase column and UV absorbance at appropriate wavelength. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow clear solution in tetrahydrofuran |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild amine-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.