China Factory Direct
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| CAS number | 63485-50-7 |
| Product name | Methyl cis-3-hydroxycyclobutanecarboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic drug intermediate for preparing biologically active cyclobutane-containing compounds | Esterification of cis-3-hydroxycyclobutylcarboxylic acid with methanol, followed by purification |
| Organic Synthesis | Employed as a chiral building block for constructing complex molecules containing cyclobutane motifs | Introduction of hydroxyl and ester groups with defined stereochemistry via asymmetric synthesis or stereoselective transformation |
| Pesticide Development | Used as a pesticide intermediate in the structural design of novel insecticides or herbicides | Served as a key fragment in multistep syntheses, with functional group transformations enabling incorporation of pharmacophores |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity (enantiomeric excess) | Chiral HPLC | Separation of enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak area ratio. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., methanol, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically to determine trace moisture. |
| Heavy Metals | ICP-MS | Multi-element detection after acid digestion, measuring total heavy metal content (e.g., Pb, Cd, Ni, Cu) at sub-pptr levels. |
| Acid Value | Acid-Base Titration | Titration with standardized KOH solution in ethanol/isopropanol; neutralization of free carboxylic acid groups. |
| Optical Rotation | [alpha]D Measurement | Measurement of plane-polarized light rotation in solution at 20 C and 589 nm, reporting specific rotation for chiral identity and purity. |
| Related Substances | HPLC-UV | Gradient HPLC with UV detection to separate and quantify structurally related impurities (e.g., diastereomers, hydrolysis products). |
| Residual Catalyst (Pd) | ICP-OES | After microwave-assisted digestion, quantitative analysis of palladium by optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination via controlled heating; identifies crystallinity and presence of impurities. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed sample using light scattering principles to generate volume-based particle size distribution. |
| Appearance | Visual Inspection | Assessment of color and physical state (e.g., white to off-white crystalline powder) against standard reference under controlled lighting. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -15.0 to -25.0 deg (c=1, in methanol) |
| Refractive Index (n20/D) | 1.430–1.450 |
| Odor | Characteristic mild ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.