5-CHLOROQUINOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 635-27-8 |
| Product name | 5-CHLOROQUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-CHLOROQUINOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-CHLOROQUINOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-CHLOROQUINOLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antimalarial agents (e.g., chloroquine, hydroxychloroquine) | Quinoline ring structure introduced via nucleophilic substitution or metal-catalyzed coupling reactions |
| Agrochemicals | Used to synthesize biologically active nitrogen-containing heterocyclic insecticides or fungicides | Serves as a key intermediate for constructing the quinoline scaffold in condensation or substitution reactions |
| Materials Science | Preparation of organic optoelectronic materials (e.g., OLED emissive layer materials) | Conjugated molecular structures built via reactions such as Suzuki coupling |
| Analytical Chemistry | Employed as a fluorescent probe or metal ion recognition reagent | Functionalized leveraging the coordinating ability and fluorescence properties of the quinoline ring |
Manufacturing Quality Control of 5-CHLOROQUINOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., quinoline, 3-chloroquinoline, 6-chloroquinoline) using gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., toluene, ethanol, dichloromethane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Separation and quantification of free chloride ions using anion-exchange column with conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria (white to off-white crystalline powder, free from visible foreign particles). |
| Loss on Drying | Gravimetric Analysis | Measurement of mass loss after drying under controlled temperature and vacuum, indicating volatile content including moisture and solvents. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to detect acidic impurities (e.g., residual HCl or carboxylic acids). |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after controlled charring and sulfuric acid treatment, followed by high-temperature incineration and weighing. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to confirm absence of chiral contamination; 5-chloroquinoline is achiral, so value should be near zero. |
Technical Specifications of 5-CHLOROQUINOLINE
| Test Item | Specification |
|---|---|
| Appearance | Brown liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | -15 to -10°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-CHLOROQUINOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-CHLOROQUINOLINE
Packaging of 5-CHLOROQUINOLINE
Industrial 5-CHLOROQUINOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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