3-Pyridinesulfonic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 636-73-7 |
| Product name | 3-Pyridinesulfonic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Pyridinesulfonic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Pyridinesulfonic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Pyridinesulfonic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for cardiovascular drugs (e.g., nicardipine) | Used in the synthesis of pyridine derivative scaffolds |
| Pharmaceuticals | Intermediate for agrochemicals and veterinary drugs | Serves as an organic synthesis raw material for sulfonic group introduction |
| Chemicals | Organic synthesis raw material | Applied in the preparation and structural modification of other fine chemicals |
Manufacturing Quality Control of 3-Pyridinesulfonic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity and Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reverse-phase chromatographic column with water-methanol or water-acetonitrile gradient elution, detected by a UV detector (254 nm). Quantification is performed via external standard or internal standard methods, effectively separating impurities and accurately determining the main component content. |
| Water Content | Karl Fischer Titration | Utilizes Karl Fischer reagent (composed of iodine, sulfur dioxide, pyridine, and methanol) that reacts quantitatively with water; endpoint is determined by potentiometric or coulometric methods. Suitable for trace water determination with precision up to ppm level. |
| Ash/Inorganic Impurities | Residue on Ignition (Charring Residue) | Sample is incinerated at high temperature (500–600°C) to constant weight; the mass of residual inorganic matter is measured to assess total inorganic impurities, in compliance with pharmacopoeial general guidelines. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion of the sample, AAS is used to determine heavy metals such as lead, cadmium, and mercury, or ICP-MS is employed for simultaneous multi-element detection with high sensitivity, meeting ICH Q3D standards. |
| pH Value | Glass Electrode Method (pH Meter) | A specified concentration solution (e.g., 1% w/v) is prepared and measured using a calibrated pH meter to ensure the acidic environment meets process requirements (typically pH 1–3). |
| Chlorides, Sulfates, and Other Ions | Ion Chromatography (IC) | Uses an anion-exchange column with conductivity detection to measure inorganic anions such as Cl⁻ and SO₄²⁻. High sensitivity makes it suitable for controlling trace impurities, in compliance with USP/EP requirements. |
| Crystal Form and Particle Size | X-ray Diffraction (XRD) + Laser Particle Size Analyzer | XRD analyzes crystal structure to confirm polymorphic consistency; laser particle size analyzer determines particle size distribution to ensure process stability and dissolution performance. |
| Ultraviolet Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Scans absorption spectra within the 200–400 nm wavelength range to identify characteristic absorption peaks (e.g., λmax ≈ 254 nm) for qualitative identification and preliminary purity assessment. |
| Volatile Organic Impurities | Gas Chromatography (GC) | Uses headspace or direct injection with a capillary column to separate residual solvents (e.g., methanol, acetonitrile), detected by FID, in compliance with ICH Q3C guidelines. |
| Nitrogen Content (Elemental Analysis) | Elemental Analyzer (CHNS Analysis) | Nitrogen content is determined after high-temperature combustion and oxidation, verifying whether the nitrogen proportion matches the theoretical value (approximately 8.5%) for the molecular formula (C₅H₅NO₃S). |
Technical Specifications of 3-Pyridinesulfonic acid
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Pyridinesulfonic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Pyridinesulfonic acid
Packaging of 3-Pyridinesulfonic acid
Industrial 3-Pyridinesulfonic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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