Z-D-GLU-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 63648-73-7 |
| Product name | Z-D-GLU-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-D-GLU-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-D-GLU-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-D-GLU-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthon for synthesizing drug intermediates containing the D-glutamic acid moiety | Protected amino acid used in peptide synthesis; incorporated into target molecules via solid-phase or solution-phase synthesis |
| Biochemical Research | Enzyme studies and construction of probes for D-amino acid metabolic pathways | Serves as substrate or inhibitor in enzyme reaction systems; CBZ protecting group must be removed prior to activity testing |
| Organic Synthesis | Chiral building block for asymmetric synthesis | CBZ protecting group is cleaved under conditions such as palladium-catalyzed hydrogenation, releasing free D-glutamic acid for subsequent reactions |
Manufacturing Quality Control of Z-D-GLU-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment using a chiral stationary phase and UV detection, resolving D- and L-glutamic acid derivatives. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in a pyridine-methanol solvent system. |
| Residual Solvents | GC-FID | Identification and quantification of common solvents (e.g., ethyl acetate, methanol) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm stereochemical integrity of the D-enantiomer. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on Mie scattering theory using a laser diffraction particle analyzer. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery and enumeration of aerobic microorganisms from a dissolved sample via filtration and agar plate incubation. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., N-CBZ-L-glutamic acid, decarboxylated products) using gradient HPLC-UV. |
Technical Specifications of Z-D-GLU-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148~152°C |
| Optical Rotation | +7.0 to +8.0° (c=1, in 1N HCl) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-D-GLU-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-D-GLU-OH
Packaging of Z-D-GLU-OH
Industrial Z-D-GLU-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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