China Factory Direct
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| CAS number | 6384-18-5 |
| Product name | dimethyl (2S)-2-aminobutanedioate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate in aspartame synthesis | Serves as a source of the aspartic acid residue and undergoes condensation with phenylalanine methyl ester to produce aspartame via chemical or enzymatic synthesis. |
| Pharmaceutical Chemicals | Building block for peptide-based drug synthesis | Undergoes selective protection and condensation reactions at its free amino and carboxyl groups for solid-phase or solution-phase peptide synthesis. |
| Food Additives | Precursor for functional sweeteners | The side-chain carboxyl group of aspartic acid is protected via esterification to generate precursors for low-calorie sweeteners. |
| Biochemistry | Substrate for enzymatic reactions | Acts as a substrate in enzymatic synthesis processes, participating in transpeptidation or hydrolysis reactions to produce specific dipeptide derivatives. |
| Chemical Synthesis | Chiral intermediate | The chiral amino group serves as a key structural unit in asymmetric or chiral-pool synthesis to construct optically active organic molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Separation on reversed-phase column followed by quantification using UV absorbance at 205 nm relative to a certified reference standard. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral L-isomer in solution at specified concentration and wavelength (589 nm). |
| Water Content | Karl Fischer titration | Electrochemical titration using iodine, sulfur dioxide, and base in methanol to quantify water based on stoichiometric reaction. |
| Residue on Ignition | Gravimetric analysis | Heating sample to 700-800 C to volatilize organic matter, then weighing inorganic residue as sulfate ash. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals after wet digestion, using lead as the toxicological marker and flame or graphite furnace AAS. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on anion-exchange column with conductivity detection, calibrated against NaCl standards. |
| Sulfate Impurity | Barium Chloride Turbidimetry | Precipitation of sulfate as BaSO4 in acidic medium; turbidity measured spectrophotometrically at 420 nm. |
| Related Substances | HPLC with gradient elution | Separation of L-aspartic acid, D-aspartic acid methyl ester, methylamine, and other process-related impurities using UV detection. |
| pH of 10% Aqueous Solution | Potentiometric pH measurement | Determination using calibrated glass electrode in a saturated aqueous solution at 25 C. |
| Melting Point | Capillary melting point apparatus | Thermal observation of solid-to-liquid transition range using standardized capillary tube method. |
| Loss on Drying | Thermogravimetric analysis (TGA) or oven drying | Weight loss measured after heating at 105 C for 2 hours under controlled atmospheric conditions. |
| Microbial Limits | Membrane filtration and plate count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial procedures. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112-116°C |
| Optical Rotation | -13.0° to -15.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.