China Factory Direct
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| CAS number | 640280-28-0 |
| Product name | 4-Bromo-3-iodobenzotrifluoride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediates for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Halogen exchange reactions; palladium-catalyzed cross-coupling (e.g., Suzuki, Heck reactions) |
| Agrochemical Intermediates | Structural building blocks for novel fluorinated insecticides and fungicides | Nucleophilic substitution; metal-catalyzed coupling reactions |
| Materials Science | Building blocks for organic light-emitting diodes (OLEDs) and organic semiconductor materials | C–N and C–C bond-forming reactions, including Ullmann coupling and Buchwald-Hartwig amination |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Volatile organic impurities are vaporized in headspace vial and quantified by GC-FID using external calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Sample digested in acid matrix, then elemental emission intensities measured at characteristic wavelengths for semi-quantitative multi-element analysis. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on ion-exchange column followed by quantitative detection via conductivity change after suppression. |
| Acid-Base Impurities | Acid-Base Potentiometric Titration | Titration with standardized NaOH or HCl solution; endpoint determined from inflection point in pH vs. titrant volume curve. |
| Residual Catalyst (Pd) | ICP-OES | After microwave-assisted acid digestion, palladium concentration determined by measuring atomic emission intensity at 247.6 nm. |
| Volatility Loss | Thermogravimetric Analysis (TGA) | Mass loss measured as function of temperature under controlled nitrogen atmosphere to assess thermal stability and volatile content. |
| Appearance | Visual Inspection (against USP <941>) | Comparison of sample in clear glass container under controlled white light against specified reference (e.g., colorless to pale yellow liquid). |
| Specific Gravity | Digital Density Meter (Oscillating U-tube) | Density calculated from resonant frequency shift of oscillating U-shaped tube filled with sample at controlled temperature. |
| Refractive Index | Abbe Refractometer | Measured by critical angle of total internal reflection at sample-prism interface at specified temperature (20 C). |
| Organic Volatile Impurities (other than solvents) | GC-MS | Identification and semi-quantification of unknown volatile/semi-volatile impurities via mass spectral library matching and extracted ion chromatograms. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.5% (GC) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545–1.555 |
| Relative Density (20°C/25°C) | 1.92–1.96 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.