1-(4-Fluorophenyl)piperazine dihydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 64090-19-3 |
| Product name | 1-(4-Fluorophenyl)piperazine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(4-Fluorophenyl)piperazine dihydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(4-Fluorophenyl)piperazine dihydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(4-Fluorophenyl)piperazine dihydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate for the synthesis of antipsychotic and antidepressant drugs | Used as a key intermediate in multistep organic synthesis, commonly applied to construct piperazine-based bioactive molecular frameworks |
| Pharmaceutical R&D | Starting material for synthesizing novel central nervous system (CNS) drugs | Functional groups are introduced via acylation, alkylation, and related reactions to build compounds with specific pharmacological activity |
| Biochemical Research | Used in structure–activity relationship (SAR) studies of piperazine compounds | Serves as a template compound in in vitro assays to evaluate binding affinity toward receptors or enzymes |
| Advanced Materials | Modifier for functional polymeric materials | Integrated into polymer backbones via polymerization to enhance thermal stability and biocompatibility |
Manufacturing Quality Control of 1-(4-Fluorophenyl)piperazine dihydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., residual piperazine, fluorobenzaldehyde derivatives) using gradient HPLC/UPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., ethanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion, per ICH Q3D requirements. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic ash content after incineration at 600–750 °C, expressed as percentage weight loss. |
| pH (1% aqueous solution) | pH Potentiometry | Measurement of hydrogen ion activity in aqueous suspension using calibrated pH electrode and buffer standards. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate. |
| Particle Size Distribution | Laser Diffraction | Analysis of dispersed particle size based on angular variation of laser light scattering intensity. |
| Microbial Limits | Membrane Filtration + Culture Enumeration | Detection and enumeration of aerobic microorganisms and specified pathogens per Ph. Eur. 2.6.12/USP <61>. |
Technical Specifications of 1-(4-Fluorophenyl)piperazine dihydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Almost white powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(4-Fluorophenyl)piperazine dihydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(4-Fluorophenyl)piperazine dihydrochloride
Packaging of 1-(4-Fluorophenyl)piperazine dihydrochloride
Industrial 1-(4-Fluorophenyl)piperazine dihydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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