2-Fluoro-5-methylbenzonitrile Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 64113-84-4 |
| Product name | 2-Fluoro-5-methylbenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 2-Fluoro-5-methylbenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-5-methylbenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-5-methylbenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antitumor agents | Used in the synthesis of kinase inhibitors or other antitumor active molecules with specific structures, typically via coupling or substitution reactions to construct the drug scaffold. |
| Pharmaceuticals | Intermediate for neurologic agents | Used in the synthesis of drugs for treating neurologic disorders, involving nitrile group transformations or further functionalization of aromatic rings. |
| Agrochemicals | Intermediate for insecticides/herbicides | Used in the synthesis of fluorinated agrochemical active ingredients, leveraging its fluoromethylbenzonitrile structure to enhance biological activity. |
| Chemicals | Building block for organic synthesis | Serves as a starting material for preparing other fine chemicals via reduction (to yield amines), hydrolysis (to yield amides or carboxylic acids), or halogenation. |
Manufacturing Quality Control of 2-Fluoro-5-methylbenzonitrile
| Milestone | Common Testing Methods | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Using a C18 reversed-phase column, with methanol-water or acetonitrile-water as the mobile phase, and ultraviolet detector (UV, 220–254 nm). The main component content is calculated using external standard method or area normalization method, suitable for quantitative analysis. |
| Impurity Profile Analysis | HPLC-UV / HPLC-MS | Gradient elution HPLC is used to separate impurities, combined with UV detection or mass spectrometry (MS) for identification of unknown impurities. It complies with ICH Q3B guidelines, used for controlling known/unknown impurity limits. |
| Water Content | Karl Fischer Titration | Using Karl Fischer reagent composed of iodine, sulfur dioxide, pyridine, and methanol, the sample's trace moisture is determined by electrochemical titration, with a precision up to ppm level. Suitable for moisture control in organic solvents. |
| Residual Solvents | Gas Chromatography (GC) | Using capillary columns (e.g., DB-624 or HP-INNOWAX), FID detector. The residual solvents such as methanol, ethanol, acetone, dichloromethane are determined according to USP/EP methods, complying with ICH Q3C standards. |
| Fluorine Content | Ion Chromatography (IC) or Oxygen Bomb Combustion + Ion Selective Electrode | After alkali fusion or oxygen bomb combustion, the sample is converted into fluoride ions, which are detected by ion chromatography or measured by fluoride ion selective electrode to ensure the fluorine content meets the molecular formula requirements. |
| Melting Point | Melting Point Apparatus | Digital melting point apparatus is used to determine the melting point range (literature value about 58–62°C), serving as a physical constant for preliminary identification and purity assessment. |
| Appearance and Color | Visual Inspection + Colorimetric Determination (APHA) | Observe that the sample is colorless to slightly yellow liquid or solid, and use a colorimeter to measure the color intensity according to APHA (Pt-Co) standard colorimetric method, ensuring product appearance consistency. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | The sample is digested, and heavy metal contents such as lead, cadmium, mercury, and arsenic are determined by AAS or ICP-MS, complying with pharmacopoeia (e.g., USP <231>) or ICH Q3D requirements for elemental impurities. |
| Inorganic Ions such as Chloride and Sulfate | Ion Chromatography (IC) or Colorimetric Method | The sample is hydrolyzed or dissolved, then Cl⁻, SO₄²⁻ and other inorganic anions are detected by IC, or limited control is performed by classical colorimetric methods (e.g., silver chloride precipitation method). |
Technical Specifications of 2-Fluoro-5-methylbenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 42–46°C |
| Identification (NMR) | Conforms to reference standard |
| Identification (IR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 2-Fluoro-5-methylbenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-5-methylbenzonitrile
Safety Information of 2-Fluoro-5-methylbenzonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Fluoro-5-methylbenzonitrile
Industrial 2-Fluoro-5-methylbenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply