4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 641569-94-0 |
| Product name | 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 641569-94-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 641569-94-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 641569-94-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for protein kinase inhibitors, used in the synthesis of anticancer drugs (e.g., imatinib analogues) | Key building block in organic synthesis, employed in Suzuki coupling, amidation, and related reaction steps |
| Pharmaceutical R&D | Used in screening and developing small-molecule inhibitors targeting tyrosine kinases such as BCR-ABL and c-KIT | Lead compound modification in high-throughput screening and structure–activity relationship (SAR) studies |
| Chemical Research | Functionalized aromatic carboxylic acid containing pyridine and pyrimidine heterocycles, used to construct complex heterocyclic systems | Starting material for multicomponent reactions, metal-catalyzed cross-coupling, and heterocycle condensation reactions |
Manufacturing Quality Control of 641569-94-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by retention time and UV response relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, DMF) via headspace GC with flame ionization detection using calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, As) after acid digestion using inductively coupled plasma mass spectrometry with isotope detection. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion of sample with sulfuric acid followed by high-temperature incineration and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus under controlled heating rate. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder via Mie scattering theory analysis of laser light diffraction pattern. |
| Bulk Density | ASTM D1895 | Determines mass per unit volume of freely settled powder using standardized cylinder and funnel method. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) by filtration, culture on selective media, and colony enumeration. |
Technical Specifications of 641569-94-0
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 641569-94-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 641569-94-0
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Industrial 641569-94-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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