3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 641571-11-1 |
| Product name | 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for JAK2 kinase inhibitors, used in the treatment of hematologic disorders such as myeloproliferative neoplasms | Acts as the core aromatic amine structural unit in pyrimidoimidazole-based JAK2 inhibitors; couples with halogenated heterocyclic fragments via cross-coupling reactions (e.g., Buchwald–Hartwig amination) |
| Agrochemicals | Structural building block for novel insecticidal and fungicidal candidate compounds | Introduces a hydrophobic–hydrogen-bonding pharmacophore containing both trifluoromethyl and imidazolyl groups; employed in structural optimization and structure–activity relationship (SAR) studies of bioactive molecules |
| Materials Science | Building block for organic optoelectronic functional materials | Serves as an amine-terminated modification component in donor–acceptor (D–A) type conjugated polymers or small molecules, used to tune HOMO energy levels and thin-film morphology |
Manufacturing Quality Control of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (e.g., white to off-white crystalline powder) under natural light or standard illumination to determine compliance with specifications. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
IR: Compare the infrared absorption spectrum of the sample with that of the reference standard; HPLC: Under specific chromatographic conditions, compare the retention time of the main peak with that of the reference substance; ¹H NMR: Confirm molecular structure based on characteristic chemical shifts and coupling constants. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with mobile phase consisting of methanol-water or acetonitrile-buffer salt system, detected by UV detector (e.g., 254 nm). Quantify the main component using external standard method; typically requires ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ gradient elution to separate the main component from potential impurities (e.g., starting materials, intermediates, degradation products). Control individual and total impurity levels using area normalization or the main component self-control method with correction factors (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with a polar capillary column (e.g., DB-624), detected by FID. Detect residual organic solvents (e.g., methanol, dichloromethane, toluene) from synthesis or purification processes, following ICH Q3C guidelines for specified limits. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Constant Weight Method | Dry the sample at 105°C until constant weight, then calculate the percentage of mass loss to assess moisture and volatile content (typically ≤0.5%). |
| Residue on Ignition | Gravimetric Method | Ignite the sample at high temperature (700–800°C), then weigh the residual inorganic matter. Used to control inorganic impurities (typically ≤0.1%). |
| Water Content | Karl Fischer Titration | Determine water content using either volumetric or coulometric Karl Fischer titration, suitable for moisture-sensitive compounds. Typically requires ≤0.5%. |
Technical Specifications of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=99.0% (LC-MS) |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Safety Information of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
| Pictograms |    |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Industrial 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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