China Factory Direct
|
|
| CAS number | 64285-73-0 |
| Product name | 3,3',5,5'-Tetramethylbenzidine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| In Vitro Diagnostics | Chromogenic detection of peroxidase and hydrogen peroxide in urine and blood, for pregnancy tests, fecal occult blood tests, etc. | Oxidation reaction with hydrogen peroxide under peroxidase catalysis, generating a soluble blue quinone-type product for quantitative colorimetric analysis |
| Environmental Monitoring | Detection of hydrogen peroxide, peroxides, and certain heavy metal ions (e.g., copper, iron) in water | Colorimetric reaction of TMB catalyzed by specific oxidants or metal ions, applied in spectrophotometric determination |
| Biomedical Research | Substrate for horseradish peroxidase (HRP) in ELISA, immunohistochemistry, and Western blotting | HRP-catalyzed reaction of TMB hydrochloride with H₂O₂ yields a soluble blue product; acid termination converts it to yellow for absorbance measurement at 450 nm |
| Food Safety Testing | Rapid screening of peroxide value, residual hydrogen peroxide, and microorganisms (e.g., peroxidase-positive bacteria) in food | Colorimetric reaction using the TMB–H₂O₂–HRP system, implemented via lateral flow strips or microplate assays for semi-quantitative or quantitative analysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold limits. |
| Loss on Drying | Gravimetric (Thermogravimetry) | Mass loss measured after drying at 105 C for 2 hours under atmospheric pressure, indicating volatile content including residual solvents and moisture. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Mass of inorganic residue remaining after controlled ignition at 600 C following sulfuric acid treatment, reflecting inorganic impurities. |
| Heavy Metals (as Pb) | AAS (Flame or Graphite Furnace) | Quantification of total heavy metals by atomic absorption spectroscopy after wet digestion and calibration with lead standard solutions. |
| Chloride Content | Potentiometric Titration | Titration with standardized silver nitrate solution using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH of Aqueous Solution | pH Potentiometry | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated pH meter with glass electrode. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water; detects trace moisture in non-aqueous matrix. |
| Organic Volatile Impurities (e.g., acetone, methanol) | GC-FID | Separation and quantification of residual solvents by gas chromatography with flame ionization detection using internal standard calibration. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as a function of angle to determine volume-based particle size distribution in suspended sample. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, using calibrated capillary method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity and identity confirmation. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 235-240 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.