N-Benzylglycine ethyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 6436-90-4 |
| Product name | N-Benzylglycine ethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Benzylglycine ethyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Benzylglycine ethyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Benzylglycine ethyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral intermediate for the synthesis of the antihypertensive drug telmisartan | N-alkylation with 2-(bromomethyl)benzimidazole under basic conditions, followed by hydrolysis and cyclization to construct the biphenyl-tetrazole scaffold of telmisartan |
| Organic Synthesis | Chiral auxiliary or amino-protecting group carrier for asymmetric alkylation, acylation, and related reactions | Benzyl group introduced onto the nitrogen atom of glycine ethyl ester to form a stable tertiary amine structure; benzyl group subsequently removed selectively (e.g., via H₂/Pd-C hydrogenolysis) to liberate the free amino group |
| Pesticide Development | Nitrogen-containing side-chain building block for structural modification of novel pyrethroid insecticides | Benzylglycine moiety introduced via coupling with haloarenes or activated esters to optimize molecular lipophilicity and target-binding activity |
Manufacturing Quality Control of N-Benzylglycine ethyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and detection of impurities (e.g., N-benzylglycine, benzaldehyde, ethyl ester hydrolysis products) using gradient elution and UV monitoring. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual ethanol, toluene, or dichloromethane per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with Karl Fischer reagent. |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein) | Neutralization of free carboxylic acid groups (e.g., from hydrolyzed ester) with standardized sodium hydroxide solution. |
| Heavy Metals | ICP-MS or ICP-OES | Quantitative determination of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion and plasma-based elemental analysis. |
| Optical Rotation | [α]D Measurement (Polarimetry) | Measurement of specific rotation at 589 nm using a sodium lamp to confirm chiral integrity and absence of racemization. |
| Residue on Ignition | Gravimetric Analysis | Weighing inorganic residue remaining after high-temperature ashing (700–800 °C) per USP <281>. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions (e.g., from HCl salt residues) using anion-exchange column or silver nitrate titration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate (USP <741>). |
Technical Specifications of N-Benzylglycine ethyl ester
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.525–1.535 |
| Odor | Characteristic ester-like odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Benzylglycine ethyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Benzylglycine ethyl ester
Packaging of N-Benzylglycine ethyl ester
Industrial N-Benzylglycine ethyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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