China Factory Direct
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| CAS number | 6443-69-2 |
| Product name | 3,4,5-Trimethoxytoluene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of anticancer agents (e.g., etoposide, teniposide) | Constructs the core drug structure via organic synthesis steps including oxidation, halogenation, or side-chain functional group transformation |
| Fine Fragrances & Flavors | Preursor for synthesizing floral- or woody-type fragrance compounds | Generates aromatic compounds with specific odor profiles through selective oxidation or alkylation reactions |
| Agrochemicals | Synthetic intermediate for certain herbicides or plant growth regulators | Introduces active functional groups via electrophilic substitution or transition-metal-catalyzed coupling reactions |
| Organic Synthesis | Used to prepare derivatives such as 3,4,5-trimethoxybenzaldehyde and 3,4,5-trimethoxybenzoic acid | Employs classical organic reactions including side-chain oxidation (e.g., chromic acid oxidation), haloform reaction, or Duff formylation |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and UV detector (e.g., 254 nm or 280 nm); quantification by external standard method or area normalization to evaluate the content of the main component. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirms molecular structure and substitution positions by comparing ¹H NMR and ¹³C NMR spectra with reference standards or literature data. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Separates volatile impurities using a capillary column; mass spectrometric detection for qualitative and quantitative identification of organic by-products or residual solvents. |
| Moisture Content | Karl Fischer Titration | Determines trace water content using volumetric or coulometric methods to ensure compliance with loss on drying or moisture limit requirements. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Sample is heated and injected via headspace; residual organic solvents (e.g., methanol, ethyl acetate) are detected using GC-FID or GC-MS. |
| Melting Point | Capillary Melting Point Apparatus | Determines the melting temperature range according to pharmacopoeial or standard methods to assess purity and crystalline form consistency. |
| Appearance and Color | Visual Color Comparison Method | Observe solid color or solution clarity under natural light or standard lighting, and compare with reference solutions. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measures total levels of elements such as lead, arsenic, cadmium, and mercury to ensure compliance with ICH Q3D or pharmacopoeial limits. |
| Loss on Drying | Oven Drying to Constant Weight | Dry the sample at specified temperature (e.g., 105°C) until constant weight; calculate percentage weight loss to reflect volatile matter or moisture content. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Scans wavelength range of 200–400 nm to confirm characteristic absorption peaks (position and intensity), aiding in identification and preliminary purity assessment. |
| Test Item | Specification |
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| Appearance | Colorless to light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.525–1.535 |
| Relative Density (20°C/25°C) | 1.070–1.090 g/cm³ |
| Odor | Characteristic aromatic |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.