4-Fluoro-3-methoxyaniline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 64465-53-8 |
| Product name | 4-Fluoro-3-methoxyaniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Fluoro-3-methoxyaniline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Fluoro-3-methoxyaniline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Fluoro-3-methoxyaniline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents (e.g., BTK inhibitors) | Diazotization-coupling and palladium-catalyzed cross-coupling reactions |
| Agrochemicals | Structural building block for novel fluorinated insecticides and herbicides | Multi-step organic synthesis, including nitration-reduction, fluorination, and methylation |
| Dyes | Used in constructing chromophore systems for high-performance azo and reactive dyes | Coupling with phenolic or amine compounds following diazotization |
| Materials Science | Building block for liquid crystal monomers and organic electroluminescent (OLED) materials | Coupling reactions, including Suzuki coupling and Ullmann condensation |
Manufacturing Quality Control of 4-Fluoro-3-methoxyaniline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of impurities (e.g., isomers, dehalogenated by-products, oxidation products) using gradient HPLC/UPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals | ICP-MS or ICP-OES | Quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry or optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of chloride ions via suppressed IC with conductivity detection, or direct titration with silver nitrate. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>, indicating crystallinity and identity. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Color Scale | Subjective visual assessment of crystalline form and color intensity compared to platinum-cobalt standards. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Measurement of aqueous slurry pH to detect acidic/basic degradation products or residual catalysts. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic residue after controlled high-temperature ashing (500–600 °C) and weighing. |
| Specific Optical Rotation | Polarimetry | Measurement of chiral purity (if applicable) using sodium D-line light; though compound is achiral, used to confirm absence of chiral contaminants. |
| Bulk Density | ASTM D1895 Method A (Tapped Density) | Gravimetric determination of mass per unit volume after standardized tapping to assess powder flow and handling properties. |
| Particle Size Distribution | Laser Diffraction (Dry Dispersion) | Analysis of particle size range (D10, D50, D90) using light scattering principles for processability and dissolution consistency. |
| Sulfated Ash | Gravimetric Analysis | Quantification of non-volatile inorganic residue after sulfuric acid treatment and ignition, per USP <281>. |
Technical Specifications of 4-Fluoro-3-methoxyaniline
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 58–62°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Fluoro-3-methoxyaniline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Fluoro-3-methoxyaniline
Packaging of 4-Fluoro-3-methoxyaniline
Industrial 4-Fluoro-3-methoxyaniline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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