China Factory Direct
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| CAS number | 644971-22-2 |
| Product name | DL-BETA-PROLINOL HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key Pharmaceutical Intermediate | Serves as a building block for pyrrolidine derivatives and participates in the synthesis of chiral drug molecules. |
| Pharmaceutical Industry | Building Block for New Drug Development | Used to synthesize biologically active heterocyclic compounds, commonly applied in constructing lead compounds containing pyrrolidine moieties. |
| Organic Synthesis | Chiral Synthesis Reagent | Employed as a chiral source or chiral auxiliary—leveraging its chiral pyrrolidine structure—to induce asymmetric synthesis reactions. |
| Chemical Reagents | Research-Grade Chemical Reagent | Applied in laboratory-scale organic synthesis reactions and drug screening studies. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to measure trace water via stoichiometric reaction with pyridine/methanol buffer. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass expressed as percentage of original sample. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion, measuring emission intensities of metal atoms excited in argon plasma. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH (1% aqueous solution) | pH Meter Measurement | Electrochemical measurement of hydrogen ion activity in a 1% w/v aqueous solution at 25 C using calibrated glass electrode. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, used to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Organic Volatile Impurities | GC-FID | Headspace or direct injection GC with flame ionization detection to quantify residual solvents per ICH Q3C guidelines. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to determine volume-based particle size distribution in dispersed dry or wet samples. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens using standardized culture media and incubation conditions per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown liquid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 75–79°C |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.