3-Hydroxy-4-methoxybenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 645-08-9 |
| Product name | 3-Hydroxy-4-methoxybenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Hydroxy-4-methoxybenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Hydroxy-4-methoxybenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Hydroxy-4-methoxybenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antihypertensive agents (e.g., methyldopa derivatives) and antimicrobial agents | O-alkylation with alkyl halides under basic conditions, or condensation with amines after conversion to the corresponding acyl chloride |
| Fine Fragrances | Used in synthesizing natural-identical fragrance compounds (e.g., vanillin derivatives) and fixatives | Aldehyde or alcohol fragrance molecules prepared via decarboxylation, oxidation, or reduction |
| Pesticides | Structural building block for fungicides and plant growth regulators | Participates in heterocycle formation reactions (e.g., condensation with hydrazines to yield triazole compounds) |
| Dyes | Applied as diazo component or coupling component in azo dyes and reactive dyes | Diazotization under low-temperature acidic conditions, followed by coupling with aromatic amines or phenols |
Manufacturing Quality Control of 3-Hydroxy-4-methoxybenzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Loss on Drying | Gravimetric Heating | Mass loss measured after drying sample at 105 C for 2 hours under controlled atmospheric conditions. |
| Residue on Ignition | Sulfated Ash Gravimetry | Sample ignited at 600-700 C after sulfuric acid treatment; residual inorganic ash weighed as percentage of original sample. |
| Heavy Metals (as Pb) | AAS (Flame or Graphite Furnace) | Quantification of total heavy metals by atomic absorption spectroscopy after acid digestion and chelation with dithizone. |
| Chloride | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Sulfate | Turbidimetry | Precipitation of sulfate as barium sulfate; quantification via measurement of turbidity at 420 nm. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with KF reagent to determine water content based on stoichiometric iodine-water reaction. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using standardized pH electrode and buffer calibration. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dispersed suspension using Mie scattering theory and laser diffraction instrument. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 C using sodium D-line (589 nm) to assess chiral purity and identity. |
Technical Specifications of 3-Hydroxy-4-methoxybenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Hydroxy-4-methoxybenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Hydroxy-4-methoxybenzoic acid
Safety Information of 3-Hydroxy-4-methoxybenzoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Hydroxy-4-methoxybenzoic acid
Industrial 3-Hydroxy-4-methoxybenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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