Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 645400-44-8 |
| Product name | Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 5KG/bag25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 645400-44-8
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 645400-44-8 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 645400-44-8
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a synthetic intermediate in the development of central nervous system (CNS) drugs, including antidepressants, anxiolytics, and psychotropic agents | Constructs the cyclopentyl scaffold via organic synthesis and introduces a tert-butoxycarbonyl (Boc) protecting group to enable targeted synthesis of the desired molecule |
| Pharmaceutical Intermediates | Used to synthesize novel targeted therapeutics or small-molecule inhibitors, particularly compounds acting on G protein-coupled receptors (GPCRs) | Applies chiral synthesis techniques, leveraging (1S,3S) stereochemistry for stereoselective construction of key intermediates to enhance product purity and biological activity |
| Chemical Research | Used as a chiral reference standard or reagent to investigate relationships between stereochemical effects and biological activity | Undergoes structural modification through multi-step reactions in the laboratory, commonly applied in structure–activity relationship (SAR) studies |
| Biopharmaceuticals | Used to build candidate molecule libraries for high-throughput screening in new drug discovery programs | Employs combinatorial chemistry approaches, using this compound as a core structural unit for derivatization to generate diverse derivative libraries |
Manufacturing Quality Control of 645400-44-8
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~200–220 nm, comparing peak area against a qualified reference standard. |
| Chiral Purity | (S,S)-Enantiomeric Excess | Chiral HPLC |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., THF, MeOH, EtOAc, heptane) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni, Pd) after acid digestion, using isotopic detection for high sensitivity and specificity. |
| Residual Palladium | ICP-MS | Specific quantification of residual Pd catalyst (common in asymmetric synthesis) via isotope-specific detection after microwave-assisted digestion. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected amine, di-Boc derivative, hydrolysis products) using gradient HPLC-UV. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid sample against established reference under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which the crystalline solid transitions to liquid, indicating purity and identity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (500–600 °C) and weighing. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at sodium D-line (589 nm) to confirm chiral integrity and batch-to-batch consistency. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory to ensure consistent handling and downstream processing. |
| Microbial Limits | Membrane Filtration & Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per Ph. Eur./USP <61> and <62>. |
Technical Specifications of 645400-44-8
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | +15.0 to +19.0° (c=1, in methanol) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 645400-44-8
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 645400-44-8
Packaging of 645400-44-8
Industrial 645400-44-8 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply